+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Does febrile proteinuria exist?

, : Does febrile proteinuria exist?. Klinische Wochenschrift 61(18): 917-922

The significance of proteinuria during febrile infectious diseases is widely underestimated, although the more marked proteinuria probably signalizes a parainfectious nephropathy rather than a functional disorder. This study shows that mild proteinuria of less than 0.65 g/24 h (normal range less than 0.3 g/24 h using the sensitive tannine-FeCl3-technique) might be caused by the elevated body temperature alone. 9 out of 18 volunteers without renal disease undergoing experimental hyperthermia of 40-41 degrees C for 1-2 h did not develop a proteinuria according to quantitative and qualitative (SDS-PAGE) measurements. In 6/18 the amount and composition of urinary proteins changed giving a glomerular type of proteinuria, possibly caused by temperature related transient glomerular alterations. In 3/18 a mild glomerulopathy existed before hyperthermia, as deduced from a glomerular pattern despite a quantitatively physiological proteinuria, leading in all 3 to pathological proteinuria during hyperthermia. In all 18 volunteers alterations reversed to normal within 12 h. Therefore, the degree of proteinuria during febrile diseases should be considered. Proteinuria of less than 0.5-1 g/24 h in adults might be explained by an altered glomerular function alone. Proteinurias exceeding this value, with a slow regressing tendency will indicate glomerular or tubulo-interstitial diseases, caused possibly by immunologic or toxic products resulting from underlying infectious disease.


PMID: 6632731

Other references

Surdam R.C.; Eugster H.P., 1976: Mineral reactions in the sedimentary deposits of the Lake Magadi region, Kenya. Geological Society of America Bulletin 87(12): 1739-1752

de Totero, D.; Tazzari, P.L.; Lauria, F.; Raspadori, D.; di Celle, P.F.; Carbone, A.; Gobbi, M.; Foa, R., 1993: Phenotypic analysis of hairy cell leukemia: "variant" cases express the interleukin-2 receptor beta chain, but not the alpha chain (CD25). Hairy cell leukemia (HCL) is a B-cell chronic lymphoproliferative disorder in which the pathologic cells show a strong expression of CD25 (interleukin-2 [IL-2] receptor alpha chain or p55). "Variant" cases of HCL, characterized by hyperl...

Takada, A.; Mochizuki, K.; Takada, Y., 1981: Influence of SK-potentiator and fibrinogen degradation products on the activation of human plasminogen by streptokinase. Thrombosis Research 22(5-6): 623-631

Aramvash, A.; Hajizadeh-Turchi, S.; Moazzeni-Zavareh, F.; Gholami-Banadkuki, N.; Malek-Sabet, N.; Akbari-Shahabi, Z., 2016: Effective enhancement of hydroxyvalerate content of PHBV in Cupriavidus necator and its characterization. This study investigated the effects of using a combination of substrates (fructose, propanol, citric acid, acetic acid, propionic acid and beef extract) on the synthesis of poly (3-hydroxybutyrate-co-3-hydroxyvalerate), which is also known as PHBV...

Schlegel, F.; Huhold, K., 1983: Uterus findings from rectal examination of cows during early pregnancy. Routine rectal exploration over a three-year period at 6-8 weeks of gestation revealed fetal death in 2.7% of cows. The amniotic sac was ruptured by rectal exploration at 32-46 days of gestation in 18 cows, which returned to oestrus after about 32...

Malyszko, J.; Zbroch, E.; Wolczynski, S.; Malyszko, J.S.; Mysliwiec, M., 2000: Leptin and serum erythropoietin in HD and CAPD patients during rHuEPO therapy. Nephrology Dialysis Transplantation 15(9): A158, September

ABDUSAMETOV.R.Kh., 1961: On the problem of antibiotic therapy of actinomycosis. Zdravookhranenie Kazakhstana 21(9): 64-68

Wortis, J., 1981: Psychiatric specialists: some numbers. Biological Psychiatry 16(11): 1005-1006

Lohmann, T.; Kellner, K.; Verlohren, H.J.; Krug, J.; Steindorf, J.; Seissler, J., 2001: Titer and combination of islet cell autoantibodies discriminate two types of latent autoimmune diabetes in adults. Diabetologia 44(Supplement 1): A 154, August

Jennings, R.B., 1951: A simple disposable apparatus for dehydration of frozen tissues. A.M.A. Archives of Pathology 52(2): 195-197