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Effect of bilateral lesions of the dentate and interpositus cerebellar nuclei on conditioning of heart-rate and nictitating membrane/eyelid responses in the rabbit


, : Effect of bilateral lesions of the dentate and interpositus cerebellar nuclei on conditioning of heart-rate and nictitating membrane/eyelid responses in the rabbit. Brain Research 305(2): 323-330

It has been shown that unilateral lesions of the medial dentate/lateral interpositus nuclear region of the cerebellum abolish the learned nictitating membrane (NM)/eyelid response of the eye ipsilateral to the lesion. The present study examined the effects of bilateral cerebellar lesions on acquisition of heart-rate conditioning (often viewed as a measure of 'conditioned fear') and both its short-and long-term effects on NM/eyelid learning and relearning. The results demonstrate that cerebellar lesions that completely and permanently abolish acquisition or retention of the somatic response (NM/eyelid) bilaterally have no effect on heart-rate conditioning. The neuronal circuits necessary for learning of the heart-rate response and for learning of the adaptive somatic response are thus in significant part different. Results are tentatively interpreted within the context of a two-process theory of aversive learning: an initial phase indexed by conditioned autonomic and 'non-specific' responses such as heart-rate and a subsequent phase of learning the specific adaptive responses.

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PMID: 6744069


Other references

Wenzel J.E.; Lindeman R.B.; Riley H.D.Jr, 1970: Renal function alterations during acute uncomplicated urinary tract infections in children. Southern Medical Journal 63(12): 1504-1505

Kontou, N.; Psaltopoulou, T.; Soupos, N.; Polychronopoulos, E.; Xinopoulos, D.; Linos, A.; Panagiotakos, D.B., 2014: The mediating effect of Mediterranean diet on the relation between smoking and colorectal cancer: a case-control study. The protective role of Mediterranean diet (MD) and the detrimental effect of smoking on colorectal cancer (CRC) have already been shown. The aim of this work was to evaluate the potential mediating effect of MD on the association between the afore...

Boorman, K.E.; Dodd, B.E., 1947: The activation of haemagglutinins by human serum. Expts. are described in which hemagglutinins are titrated using both saline and normal human serum as diluents and the titration values obtained with each diluent compared. The results show that normal human serum contains a property which causes...

Schutt, Hartwig., 1993: The genus Dreissena in the Quarternary of Anatolia Bivalvia Eulamellibranchiata Dreissenacea Die Gattung Dreissena im Quartar Anatoliens Bivalvia Eulamellibranchiata Dreissenacea. Archiv fuer Molluskenkunde, 122: 323-333

Douglas, R.Duane.; Hopp, C.D.; Augustin, M.A., 2015: Dental students' preferences and performance in crown design: conventional wax-added versus CAD. The purpose of this study was to evaluate dental students' perceptions of traditional waxing vs. computer-aided crown design and to determine the effectiveness of either technique through comparative grading of the final products. On one of t...

Antier, D.; Brosnan, M.; Carswell, H.; Hamilton, C.; Macrae, I.; Reid, J.; Dominiczak, A., 2000: Effects of age and hypertension on superoxide production in the rat brain. Journal of Hypertension 18(Suppl 4): S208

Evans, S.M.; Walsh, S.L.; Levin, F.R.; Foltin, R.W.; Fischman, M.W.; Bigelow, G.E., 2001: Effect of flupenthixol on subjective and cardiovascular responses to intravenous cocaine in humans. The effects of oral flupenthixol and intramuscular (i.m.) flupenthixol decanoate in combination with intravenous (i.v.) cocaine were evaluated in male cocaine abusers. Participants resided at an inpatient research unit for 27 days followed by an 1...

Kudó, K.; Fujioka, Y., 1975: Clinical studies on mandibular bone grafts. I. Prognosis in 28 cases of bone grafting. Nihon Koku Geka Gakkai Zasshi 21(2): 180-187

Kiely, J.M.; Noh, J.H.; Graewin, S.J.; Pitt, H.A.; Swartz-Basile, D.A., 2005: Altered intestinal motility in leptin-deficient obese mice. Introduction. Leptin is produced by adipocytes and causes satiety by regulating hypothalamic neurotransmission and energy expenditure. Leptin functions through the active long form of its receptor, which is expressed throughout the gastrointestina...

Zeiger E., 1980: Mammalian cell mutagenesis in a mutagen screening program. Hsie, A. P. O'Neill And V. K. Mcelheny (ed.). Banbury Report, 2. Mammalian Cell Mutagenesis: The Maturation Of Test Systems; Proceedings Of A Meeting, May . Xiv 504p. Cold Spring Harbor Laboratory: Cold Spring Harbor, N.y., Usa. Illus: P145-154, 1979