+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Effects of morphine, beta-endorphin and naloxone on catecholamine levels and sexual behavior in the male rat

, : Effects of morphine, beta-endorphin and naloxone on catecholamine levels and sexual behavior in the male rat. Pharmacology, Biochemistry, and Behavior 13(3): 435-441

Intraperitoneal administration of the opiate antagonist naloxone hydrochloride (30 mg/kg) to sexually experienced male rats caused a significant reduction in mount and intromission latencies, number of mounts preceding ejaculation and ejaculation latencies. Intraperitoneal adminstration of naloxone (30 mg/kg) also stimulated persistant non-copulators to begin mating and to ejaculate within a twenty minute test period. Conversely, intraperitoneal administration of morphine sulphate (6 mg/kg) as well as intraventricular injection of the endogenous opiate beta-endorphin (6 micrograms) produced a complete loss of copulatory behavior in male rats. The deficit in sexual behavior induced by beta-endorphin was correlated with a significant increase in hypothalamic norepinephrine levels. It is suggested that the endogenous opiates may be involved in the mediation of sexual behavior via an interaction with central catecholaminergic systems.


PMID: 6252562

Other references

Prento P., 1980: The effect of histochemical methylation on the phosphate groups of nucleic acids interpretation of the absence of nuclear basophilia. The effect of hot methylation (HCl methanol) on [pig intestinal cell] nuclear stainability was investigated in order to determine whether the progressive loss of basophilia is due to methylation of the diester phosphate groups of nucleic acid. DNA...

Schneider, P.; Reiners, C.; Cointry, G.R.; Capozza, R.F.; Ferretti, J.L., 2001: Bone quality parameters of the distal radius as assessed by pQCT in normal and fractured women. The aim of this study was to test the ability of some indicators of different aspects of bone quality (assessed by peripheral quantitative computed tomography in the distal radius) to discriminate between fractured and nonfractured individuals. Th...

Maier, B.; Chen, I.; Dubnau, D.; Sheetz, M.P., 2004: Bacterial DNA uptake observed on a single molecule level. Bacteria can acquire genetic diversity, including antibiotic resistance and virulence traits, by horizontal gene transfer. In particular, many bacteria are naturally competent for uptake of naked DNA from the environment in a process called transf...

Anonymous, 2015: My doctor recommended I try cognitive behavioral therapy to help treat my depression. What is it, and how can it help me?. Dukemedicine Healthnews 20(1): 8-8

H.D.D.; Rota T.R.; Schooley R.T.; Kaplan J.C.; Allan J.D.; Groopman J.E.; Resnick L.; Felsenstein D.; Andrews C.A.; Hirsch M.S., 1986: Isolation of htlv iii from csf and neural tissues of patients with aids related neurological syndromes. Gluckman, J C And E Vilmer (Ed ) Acquired Immunodeficiency Syndrome; Plenary Session Lectures And Key Note Communications Of The International Conference on Aids, Paris, France, June 23-25, 298p Editions Scientifiques Elsevier: Paris, France; Elsevier: New York, New York, Usa Illus Paper 211-218

Z.Mingguo, 1997: Recent advances in the study of granulites from the North China Craton. International Geology Review 39(4): 325-341

Gosliner T.M., 1981: Cuthona phoenix new species of tergipedid nudibranch from the coast of california usa. Journal of Molluscan Studies 47(PART 2): 200-205

Heerz, Daniel., 1999: Caryophyllidae Blasenkorallen. DATZ. Juni; 526: 28-30

Wellburn, Gv, 1981: Logging in mountainous regions. XVII IUFRO World Congress Japan 1981 International Union of Forest Research Organizations = Internationaler Verband Forstlicher Forschungsanstalten = Union internationale des instituts des recherches forestieres: 178

Janbon, M.; Bertrand, A., 1958: Swineherd's disease; leptospirosis of porcine origin due to Leptospira pomona & Leptospira mitis J. (Leptospira hyos). La Revue du Praticien 8(29): 3365-3366