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Effects of motor cortex stimulation on spinal interneurones in intact man

, : Effects of motor cortex stimulation on spinal interneurones in intact man. Experimental Brain Research 54(2): 382-384

The effect of a descending corticospinal volley on a spinal inhibitory pathway, has been studied in five intact human subjects. Approximately 63% inhibition of the H-reflex evoked in wrist and finger flexor muscles, was produced by motor threshold stimulation of the radial nerve. When a submotor threshold cortical shock was given 2 to 4 ms before the H-reflex, this inhibition was reduced to approximately 38%. The timing of this effect is compatible with either a monosynaptic or disynaptic corticospinal tract projection onto the spinal inhibitory interneurone.


PMID: 6723858

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