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Effects of n-alkanols on the membrane fluidity of chick embryo heart microsomes

, : Effects of n-alkanols on the membrane fluidity of chick embryo heart microsomes. Biochimica et Biophysica Acta 600(2): 263-269

The n-alkanols from butanol through octanol are membrane perturbing agents that fluidize the microsomal membranes of 20-day-old chick embryo hearts as measured by the fluorescence depolarization of 1,6-diphenylhexatriene. In terms of the aqueous concentrations of n-alkanols the fluidizing effect increases with increasing number of carbons per n-alkanol. In terms of the membrane concentrations of n-alkanols the fluidizing effect is roughly equivalent for all the n-alkanols studied.


PMID: 7407114

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