geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Effects of naloxone on insulin-induced release of pituitary hormones


, : Effects of naloxone on insulin-induced release of pituitary hormones. Journal of Clinical Endocrinology and Metabolism 53(1): 206-208

To evaluate the role of endogenous opiates on the regulation of the pituitary hormonal stress response, we have studied in six normal subjects the insulin-induced secretion of PRL, GH, and ACTH with and without naloxone, a specific opiate antagonist. During hypoglycemia, naloxone infusion reduced plasma PRL levels at 90 min, lowered the overall GH response, and enhanced that of ACTH. These observations suggest that endogenous opiates have a modulatory role in the stress-induced secretion of pituitary hormones.

US$19.90

PMID: 6263936

DOI: 10.1210/jcem-53-1-206


Other references

Barnils, N.; Mesa, E.; Muñoz, S.; Ferrer-Artola, A.; Arruga, J., 2007: Response to idebenone and multivitamin therapy in Leber's hereditary optic neuropathy. Archivos de la Sociedad Espanola de Oftalmologia 82(6): 377-380

Bergmann, E., 1975: The energy limit for continuous performance in forest work. Discusses maximum work and standard work (in kcal) tolerable per minute, hour and day, the average % of working hours in which heavy physical work is done, and the amount of rest periods required to ensure that the ergonomic effort does not exceed...

Krieglstein, J., 1969: On the importance of protein-binding for the uptake of promazine in the liver. Naunyn-Schmiedebergs Archiv für Experimentelle Pathologie und Pharmakologie 263(1): 273-274

Gelfand, M.L.; Begner, J.A., 1981: Clearing of pulmonary metastases after nephrectomy for hypernephroma. Bulletin of the New York Academy of Medicine 57(5): 378-381

Zhurakovskaya G.P.; Petin V.G., 1988: The degree of synergetic effects under a simultaneous action of yeast cells of uv light and hyperthermia related to the uv intensity. In experiments with wild-type diploid yeast cells of Saccharomyces cerevisiae it was shown that the definite temperature interval revealed the synergistic effect under simultaneous action of UV-irradiation and hyperthermia. The correlation between...

Introcaso Antonio, 1980: New gravimetric interpretation of the Salado Basin, Argentina. International Geological Congress, Abstracts--Congres Geologique Internationale, Resumes 26, Vol

Anonymous, 2013: Enhanced NFkappaB Activity Impairs Vascular Function through PARP-1, SP-1 and COX2-Dependent Mechanisms in Type 2 Diabetes. Type 2 diabetes (T2D) is associated with vascular dysfunction. We hypothesized that increased nuclear factor kappa B (NFB) signaling contributes to vascular dysfunction in T2D. We have treated type 2 diabetic (db<sup>–</sup>/db&l...

Vogt, H., 1974: Cercyon - Studien 2. Eine neue Cercyon - Art aus Osterreich. Entomologische Blaetter fuer Biologie und Systematik der Kaefer, 703: 190-192

Xu, H.; Hu, J-Jia.; Humphrey, J.D.; Liu, J-Charn., 2011: Automated measurement and statistical modelling of elastic laminae in arteries. Structural features of elastic laminae within arteries can provide vital information for both the mechanobiology and the biomechanics of the wall. In this paper, we propose, test and illustrate a new computer-based scheme for automated analysis of...

Epelbaum, J.; Bluet-Pajot, M.T.; Llorens-Cortes, C.; Kordon, C.; Mounier, F.; Senut, M.C.; Videau, C., 1990: 125I-[Tyr0,D-Trp8]somatostatin-14 binding sites in the locus coeruleus of the rat are located on both ascending and descending projecting noradrenergic cells. Radioautographic determinations of 125I-[Tyr0,D-Trp8]somatostatin-14 (125I-SRIF) binding sites were performed on frozen serial sections of the locus coeruleus (LC) of control rats and of rats subjected to either bilateral microinjections of 6 hydr...