+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Effects of naloxone on regional norepinephrine content of the rabbit urinary bladder after electrical pelvic floor stimulation

, : Effects of naloxone on regional norepinephrine content of the rabbit urinary bladder after electrical pelvic floor stimulation. Urology 45(4): 711-714

Effect of opioid blockade on regional norepinephrine content of the rabbit urinary bladder was investigated under electrical pelvic floor stimulation. Norepinephrine content of the bladder body and base of the rabbit was estimated by high-performance liquid chromatography in the following four subgroups: control group; group 1, treated by electrical stimulation; group 2, treated by naloxone alone; and group 3, treated by electrical stimulation and naloxone. Intravenous administration of naloxone (group 2) caused depletion of norepinephrine content in the bladder body (P < 0.001). Norepinephrine content in the bladder base was also reduced, although this difference was not statistically significant. Electrical stimulation to the pelvic floor musculature (group 1) increased norepinephrine content both in the bladder base and the body (P < 0.01). Such a norepinephrine elevation disappeared in the rabbit treated by electrical stimulation plus naloxone (group 3). Norepinephrine content of this group was almost the same as those treated by naloxone alone. Opioid blockade appeared to block the hypogastric nerve activation induced by electrical pelvic floor stimulation.


PMID: 7716859

DOI: 10.1016/S0090-4295(99)80072-7

Other references

Currell, A.; Munn, E., 1970: The influence of anions on the activity of a microsomal (Na+ + K+)-ATPase preparation from sheep rumen epithelium. Journal of physiology: 210 (2) 106P-107P

Dempster, E.R.; Lerner, I.M., 1947: The optimum structure of breeding flocks. I. Rate of genetic improvement under different breeding plans. II. Methods of determination. AN investigation of the expected rates of gain in the production index under various age distributions of the breeding flock reveals that greater efficiency is obtained by a more widespread use of younger birds. The optimum plan investigated is on...

Kuhlmann W.D.; Schied P.; Fedde M.R., 1976: Intra pulmonary receptors in lizard sensitivity to carbon di oxide. Transactions of the Kansas Academy of Science 79(3/4): 103

Chessex R.; Delaloye M.; Muller J.; Weidmann M., 1975: Evolution of the volcanic region of Ali Sabieh (T. F. A. I.), in the light of K-Ar age determinations. Pages 221-227 1975

Hussain, N.; Natarajan, S., 2003: Results of photodynamic therapy for ipcv. Aim: To evaluate the role of PDT for IPCV with Foveal involvement Materials and Methods: Eyes with IPCV with foveal involvement were included. Patients underwent Routine ophthalmic examination. HRA- FFA/ICGA and OCT were performed pretreatment and...

Prasad, P.; Bilgrami, R.S., 1984: Effect of phenolic compounds on the growth and sporulation of Curvularia lunata (Wakker) Boedijn and Helminthosporium tetramera McKinny. Phloroglucinol, pyrocatechol, 8-hydroxyquinoline and m-hydroxybenzaldehyde inhibited both processes in C. lunata [Cochliobolus lunatus] and H. [Drechslera] tetramera, especially at higher concn.

Karaoz, Süreyya., 2004: Change in nursing students' perceptions of nursing during their education: the role of the Introduction to Nursing course in this change. This study was performed to investigate the changes in students' perceptions of nursing during their education and to evaluate the role of an Introduction to Nursing course in this change. This quasi-experimental study was conducted on 39 nur...

Ellman, A.G.; Garito, J.C., 2003: Electrosurgical blade electrode. An improved electrosurgical electrode for removing cancerous tissue and lesions. The electrosurgical electrode comprises a flat round blade having a flat end configured to be held in a scalpel handpiece of the type described in U.S. Pat. No. 4,754...

Morin, C.M.; Bélanger, L.; Bastien, Célyne.; Vallières, A., 2004: Long-term outcome after discontinuation of benzodiazepines for insomnia: a survival analysis of relapse. Discontinuation of benzodiazepine (BZD) treatment for insomnia can be a difficult task. Cognitive-behavior therapy (CBT) for insomnia, combined with a supervised medication taper, can facilitate withdrawal but there is limited evidence on long-ter...

Corcos, A.; Monaghan, F., 1992: Frank Azor Spragg, foremost Michigan plant breeder and genetics teacher. Michigan academicianng 24(3): 503-510