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Effects of naloxone therapy on hemodynamics and metabolism following a superlethal dosage of Escherichia coli endotoxin in dogs


, : Effects of naloxone therapy on hemodynamics and metabolism following a superlethal dosage of Escherichia coli endotoxin in dogs. Surgery, Gynecology & Obstetrics 152(2): 159-162

Experiments were done upon anesthetized and unanesthetized dogs given endotoxin only, endotoxin plus naloxone or naloxone only. Dogs given endotoxin and treated with naloxone showed marked hemodynamic and metabolic improvements compared with the dogs given endotoxin only. Beneficial effects of naloxone treatment following the administration of endotoxin are attentuated hypotension, hemoconcentration and acidosis and prevention of hypoglycemia. Results of mortality studies in unanesthetized dogs given endotoxin suggest that naloxone treatment increases the survival time.

US$29.90

PMID: 6782687


Other references

Cox, J.E., 1969: Quality measurements of some common orange varieties. Tables are presented showing the juice content, total soluble solids and anhydrous citric acid content of the varieties Hamlin, White Siletta and Parramatta on both trifpliata and rough lemon rootstocks, and of 21 varieties on trifoliata rootstock...

Korolev V.G., 1981: Lethal and mutagenic effects of decay of iodine 125 incorporated into cells of the yeast saccharomyces cerevisiae. The lethal and mutagenic effects and the nature of mutations induced by 125I decay in the 125I-deoxyuridinemonophosphate (125IdUMP) form were studied. The efficiency of inactivation per 125I decay in DNA is 0.23 .+-. 0.08. The efficiency of inacti...

Jankowski, W.; Gieldanowski, J.; Birecki, W., 1962: Effect of some vasoconstrictor drugs on the microphonic potential of the cochlea. Otolaryngologia Polska 16: 321-329

Velasco, F.; Molina-Negro, P.; Velasco, M., 1972: Electric stimulation of the human subthalamus. Archivos de Investigacion Medica 3(1): 11-26

Van Schoore, Gégory.; Mendive, F.; Pochet, R.; Vassart, G., 2005: Expression pattern of the orphan receptor LGR4/GPR48 gene in the mouse. Leucine-rich G-protein-coupled Receptors (LGR) constitute a subfamily of receptors related to glycoprotein hormone receptors. Amongst them, LGR4, LGR5 and LGR6 form a cluster for which natural agonists are still unknown. By an extensive gene trapp...

Cotton, R.T., 1962: Flour mill sanitation-early control of insect pests pays. The most important source of infestation in flour mills originates from grain brought in for milling. Spring brings heightened activity of insects in all stored grain, hence it is desirable to review and intensify the sanitation program in the mil...

Roberts, J.M., 1971: The antibacterial sensitivity test: boon or window dressing?. Journal of the American Osteopathic Association 70(7): 716-718

Bonenfant, J.L.; Auger, C., 1971: Professor Carlton Auger (1912-1970). Laval Medical 42(5): 423-427

Virtue, R.W.; Payne, K.W.; Caranna, L.J.; Gordon, G.S.; Rember, R.R., 1958: Observations during experimental and clinical use of fluothane. Anesthesiology 19(4): 478-487

Couvreur, J., 1953: Cardiac hypertrophies in infants. France Medecine 16(12): 17-24