+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Effects of neomycin on the waveform of auditory-evoked brain stem potentials in dogs

, : Effects of neomycin on the waveform of auditory-evoked brain stem potentials in dogs. American Journal of Veterinary Research 41(7): 1077-1081

Neomycin sulfate was administered intravenously to eight mixed-breed dogs at a dosage of 30 mg/kg/day for as long as 50 days. Auditory-evoked brain stem potentials (AEBP) were recorded from the dogs three times a week. The AEBP amplitudes and latencies from the eight treated and the eight control dogs were compared. All treated dogs eventually exhibited an isoelectric AEBP. The time required for the AEBP waveform loss to occur in the treated dogs varied between 22 and 50 days. The AEBP waveforms were still isoelectric when measured as long as 150 days after neomycin administration was stopped. The fact that AEBP did not return would tend to support the findings of others that the loss of the receptors in the inner ear, due to neomycin toxicity, is permanent. The results of this electrophysiologic study indicate that the organ of Corti (organum spirale) is the site of pathologic changes in the auditory system that result from neomycin treatment.


PMID: 7436102

Other references

Liu Dongsheng; Wang Kelu, 1964: Some problems of Quaternary sequence of Northern China. Pages 65-76 1964

Brenguier, F.; Kowalski, P.; Staudacher, T.; Ferrazzini, V.; Lauret, F.; Boissier, P.; Catherine, P.; Lemarchand, A.; Pequegnat, C.; Meric, O.; Pardo, C.; Peltier, A.; Tait, S.; Shapiro, N.M.; Campillo, M.; Di; Muro, A., 2012: First results from the UnderVolc high resolution seismic and GPS network deployed on Piton de la Fournaise Volcano. Seismological Research Letters 83.1

Mons Francis; Horowicz Leon; Babour Kamal, 1984: Multioffset VSP profiling. A methodology is presented for the processing of 2-D multioffset or "walkaway" profiles in the vicinity of a borehole. The technique aims at combining the advantages of continuous surface seismic profiling with those of borehole seismics...

Pana, G.I.; E.A., 1961: The fatigue resistance of Fir. Describes (with scale drawings) a machine specially designed to test this property; the shape and size of test pieces; and methods of determining the influence of the three factors under study. Tests showed that fatigue resistance diminished with...

Delamaire, M.; L.B.rre, C.I.; Dauriac, C.; L.P.ise, P.Y.; Beauplet, A., 1998: Fatal haemolysis following allogenic peripheral blood stem cells transplantation. Vox Sanguinis 74(SUPPL 1): 1533, June

Mardon A.A., 1990: Utilization of North America Air Defense (NORAD) radars to detect high atmosphere meteors for the purpose of recovery of meteorites. Meteoritics 25(4): 382

Morán-López, R.; Pérez-Bote, J.L.; D.S.lva, E.; Perales Casildo, A.B., 2012: Hierarchical large-scale to local-scale influence of abiotic factors in summer-fragmented Mediterranean rivers structuring effects on fish distributions, assemblage composition and species richness. Summer rainfall shortage and low or no flows in Mediterranean rivers make it difficult for fish to attain their final preferenda and hinder the assembling of fish communities. We investigated in this study the degree to which large-scale features...

Sciacca, V.; Caruso, F.; Beranzoli, L.; Chierici, F.; D.D.menico, E.; Embriaco, D.; Favali, P.; Giovanetti, G.; Larosa, G.; Marinaro, G.; Papale, E.; Pavan, G.; Pellegrino, C.; Pulvirenti, S.; Simeone, F.; Viola, S.; Riccobene, G., 2016: Annual Acoustic Presence of Fin Whale (Balaenoptera physalus) Offshore Eastern Sicily, Central Mediterranean Sea. In recent years, an increasing number of surveys have definitively confirmed the seasonal presence of fin whales (Balaenoptera physalus) in highly productive regions of the Mediterranean Sea. Despite this, very little is yet known about the routes...

Vandow, E.S.; Knapp, S.E., 1963: New York Hospitals Join Addiction Fight. Modern Hospital 101: 115-116

Token, I.B., 1962: Electron microscopic studies of the fertilization process A review with 48 references. Arkh Anat Gistol I Embriol 43(8): 101-114