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Effects of neonatal administration of 5,7-dihydroxytryptamine on locomotor activity

, : Effects of neonatal administration of 5,7-dihydroxytryptamine on locomotor activity. Psychopharmacology 77(2): 114-116

Neonatal rats treated on day 3 of life with 50 or 100 micrograms 5,7-dihydroxytryptamine exhibited long-lasting selective depletions of serotonin (5-HT). The 5-HT depletions produced a shift in the peak in locomotor activity from its normal occurrence at 15 days of age to later days of age. The observation that the decreases in activity after the peak were delayed, rather than eliminated, suggests that the inhibition of locomotor activity produced by 5-HT may be of transient importance in the developing rat. The transience of the inhibition may be the result of the continuing development of nonserotonergic systems during this time period that are involved in the regulation of activity.


PMID: 6812128

Other references

Lankisch P.G.; Buschmann H.; Otto J.; Schroeder K.; Koop H., 1986: Correlation of enzyme elevation and clinical course of acute pancreatitis. Digestive Diseases & Sciences 31(10): 1138

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Cheng, T.O., 1975: Non-invasive techniques in the evaluation of the patient with coronary heart disease. Angiology 26(11): 820-836

Cranwell, M.P.; Gibbons, J.A., 1986: Tick-borne fever in a dairy herd. An outbreak of tickborne fever in July 1982 in a dairy herd in South Wales is reported. All the 72 milking cows were depressed, some had drooping ears and others a slight ocular discharge. Many cows were pyrexic and there was a severe reduction in...

Mwange, K.N'Koma.; Hou, H-Wei.; Cui, K-Ming., 2003: Relationship between endogenous indole-3-acetic acid and abscisic acid changes and bark recovery in Eucommia ulmoides Oliv. after girdling. Eucommia ulmoides (Eucommiaceae), a traditional Chinese medicinal plant, is often subjected to severe manual peeling of its bark. If the girdled trunk is well protected from desiccation, new bark forms within 1 month. It has been proposed that phy...

Yamakawa, Y.; Forslund, O.; Chua, K.L.; Dillner, L.; Boon, M.E.; Hansson, B.G., 1994: Detection of the BC 24 transforming fragment of the herpes simplex virus type 2 DNA in cervical carcinoma tissue by polymerase chain reaction. The polymerase chain reaction (PCR) was used to investigate samples from Indonesian and Swedish patients with cervical intraepithelial neoplasia grade III (CIN III), squamous cell carcinoma or adenocarcinoma of the cervix for the presence of a tra...

Cheng, S.; Yang, P.; Guo, L.; Lin, J.; Lou, N., 2009: Expression of multi-functional cellulase gene mfc in Coprinus cinereus under control of different basidiomycete promoters. Multi-functional cellulase gene mfc was expressed in Coprinus cinereus under naturally non-inductive conditions using three heterologous promoters. Endo-beta-1,4-glucanase expression was achieved in solid and liquid media with promoter sequences f...

Hecht A.D., 1982: Drought in the great plains usa history and societal implications. American Association for the Advancement of Science Abstracts of Papers of the National Meeting 148: 14