geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Effects of neonatal undernutrition and cold stress on behavior and biochemical brain parameters in rats


, : Effects of neonatal undernutrition and cold stress on behavior and biochemical brain parameters in rats. Journal of Nutrition 111(6): 1103-1110

This study was conducted to investigate the separate and combined effects of neonatal undernutrition (U) and cold stress (S) on the behavioral and cerebral development of postweaning rats. A severe U was imposed by feeding dams a low protein diet. Postweaning all pups were fed a control diet. S consisted of daily exposure to 5 degrees for 3 minutes from day 2 to 11. Behavioral data show that U animals, stressed (S) + nonstressed (NS), exhibited a significant deficit in reversal learning of T-maze at 21 days, an enhanced passive avoidance response, but no difference in active-avoidance at 35 days when compared to controls of the same age. S had no effect on behavior development. At death (110 days), the brains were dissected into five sections and assay for acetylcholinesterase (AChE) and cholinesterase (ChE) activities. Brain weights of U animals (NS + S) were significantly lower in all sections except dorsal cortex (DC). AChE and ChE activities were significantly higher in all sections (except DC) of U animals relative to controls. S resulted in lower cerebellar weight and ChE:AChE ratios in some sections. Our results suggest a delayed behavioral maturation in U animals and an association between early postweaning behavior and brain parameters in adult rehabilitated animals.

US$29.90

PMID: 7241231


Other references

Smith, L.J.; Guy, R.I., 1952: U.S. Naval Hospital Corpsmen and radiologic defense. Medical Technicians Bulletin 3(4): 145-150

Putnam Peter E.; Klovan J.E.; Hedinger A.S.; Hopkins J.C.; Ward G.S., 1995: The Mississippian succession in the plains region of southwestern Alberta and northwestern Montana; stratigraphic and structural architecture, trapping styles and future opportunities. CSPG Reservoir: , Pages 3-4. 1995.

Chang Y I.; Reineccius G.A., 1990: Interaction of beta cyclodextrin with enantiomers of limonene and carvone. The inclusion complexes of .beta.-cyclodextrin with two pairs of chiral flavor compounds, limonene and carvone, were used to evaluate the chiral interaction. Thermal transition was examined by DSC and crystalline properties by x-ray diffractometry...

Bosemani, T.; Poretti, A.; Benson, J.E.; Meyer-Heim, A.; Huisman, T.A.G.M., 2015: Clinicoradiological correlation of scoliosis in children with Jarcho-Levin and Escobar syndromes: associated "flat bone or wing-like" imaging findings. Congenital or early onset scoliosis may be the lead clinical feature in several rare syndromes. In this paper, we present the imaging findings in two children with early onset scoliosis related to the Jarcho-Levin and Escobar syndromes and an osse...

Chen, J.D.; Pan, J.; McCallum, R.W., 1995: Clinical significance of gastric myoelectrical dysrhythmias. Normal rhythmic myoelectrical activity of the human stomach is 3 cpm, regulating gastric contractile activity. Dysrhythmia in gastric myoelectrical activity is found to be associated with functional disorders of the stomach. Gastric dysrhythmias a...

Delogu G.; Testore G.; Balbi G.; Casula M.A.; Cascioli C.; Signore L., 1985: Laboratory investigation of the hch hygroscopic condenser humidifier edith as an antimicrobial filter against pseudomonas aeruginosa. Acta Anaesthesiologica Italica 36(2): 263-266

Hisamitsu, T.; Ohata, H.; Kawanishi, T.; Ishikawa, A.; Momose, K., 1997: Effect of veratridine on Ca-2+ release from intracellular stores coupled with reverse mode action of Na+/Ca-2+ exchanger in cultured smooth muscle cells. Japanese Journal of Pharmacology 73(SUPPL 1): 283P

Veloso, H.P., 1959: Ground relief as a determining factor in Anopheline distribution in the bromeliad-malaria region of Brazil. The following is substantially the author's summary of the results of observations in the Brazilian State of Santa Catarina on the distribution in relation to topography of the members of the subgenus Kerteszia of Anopheles that breed in wate...

Nellist, M.E.; Hughes, M., 1973: Physical and biological processes in the drying of seed. Research of biological and engineering interest on seed drying is reviewed. Moisture content is defined and reference made to standard methods of determination and the differing properties of freshly harvested, re-moistened and frozen seeds. Relat...

Duru, F.; Gümrük, F.; Gürgey, A., 1994: Vacuolated white blood cells in thalassemia major. We report a case of thalassemia major in which severe cytoplasmic vacuolization was seen in white blood cells as well as in their precursors. Cytochemical examination of the vacuoles revealed Sudan Black staining. Consequently, we believe that our...