geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Effects of nialamide on responses of dog isolated arteries to tyramine and transmural electrical stimulation


, : Effects of nialamide on responses of dog isolated arteries to tyramine and transmural electrical stimulation. General Pharmacology 15(1): 19-24

In dog mesenteric arteries, nialamide (10(-5) M), a monoamine oxidase inhibitor, potentiated contractile response to tyramine but not to noradrenaline or transmural electrical stimulation (TES). Bretylium, desipramine or prior reserpinization inhibited the potentiating action of nialamide on the tyramine-induced contraction. Contractions induced by octopamine were not reduced by prior reserpinization. In the coronary artery, relaxing responses to tyramine were potentiated but those to noradrenaline and TES were not potentiated by nialamide. In the cerebral artery, nialamide failed to potentiate tyramine-induced contraction. The functional role of intraneuronal monoamine oxidase in sympathomimetic effects is discussed.

US$29.90

PMID: 6421649


Other references

Goulian M.; Goulian S.H.; Codd E.E.; Blumenfield A.Z., 1973: Properties of oligo deoxy nucleotides that determine priming activity with escherichia coli dna polymerase i. Biochemistry 12(15): 2893-2901

Repp B.H.; Milburn C.; Ashkenas J., 1983: Duplex perception confirmation of fusion. Duplex perception, the simultaneous perception of a speech syllable and of a nonspeech chirp, occurs when a single formant transition and the remainder (the base) of a synthetic syllable are presented to different ears. Two experiments were conduc...

Bauschlicher, C.W.; Bucholz, E.W.; Haskins, J.B.; Monk, J.D.; Lawson, J.W., 2017: Phenolic Polymer Solvation in Water and Ethylene Glycol, II: Ab Initio Computations. Ab initio techniques are used to study the interaction of ethylene glycol and water with a phenolic polymer. The water bonds more strongly with the phenolic OH than with the ring. The phenolic OH groups can form hydrogen bonds between themselves....

Iwarson, S.; Martinell, J.; Trollfors, B., 1980: Liver function during treatment with cefuroxime. The liver function was studied in 15 patients before and during treatment with cefuroxime. Four elderly patients had a prolonged half-life of galactose at admission but they all showed declining values during the cefuroxime treatment. Only in one...

Munro, I.R., 1982: Combining facial osteotomies for esthetic and occlusal change. Clinics in Plastic Surgery 9(4): 457-477

Torzilli, P.A.; Rose, D.E.; Dethmers, D.A., 1982: Equilibrium water partition in articular cartilage. Water partition between the interstitial fluid in articular cartilage and an external bathing solution was found using a new in-situ method. This consisted of measuring the concentration of radioactive water allowed to diffuse through the articula...

Joyard J.; Grossman A.; Bartlett S.G.; Douce R.; Chua N H., 1982: Characterization of envelope membrane poly peptides from spinach chloroplasts. Chloroplast envelope polypeptides from spinach were separated into several fractions on the basis of their solubility in a mixture of chloroform/methanol (2:1, vol/vol) or in 0.1 N NaOH. Using a simple 2 dimension procedure for gel electrophoresis...

Pedersen, F.K.; Hertz, H.; Lundsteen, C.; Platz, P.; Thomsen, M., 1977: Indication of primary immune deficiency in Fanconi's anemia. A girl with various congenital malformations developed pancytopenia and hypoplastic bone marrow at the age of 6 yr. A chromosome study of lymphocytes showed numerous breaks, gaps and rearrangements, allowing the diagnosis of Fancoli's anemia....

Chaki, S.; Steckler, T.; Ashton, D.; Kennis, L.; Nakazato, A.; Langlois, X., 2002: R278995/cra0450, a novel selective crh1 receptor antagonist receptor binding, signal transduction, functional activity and ex vivo autoradiography. Dysregulation of the CRH system has been suggested to play an important role in anxiety and depression. CRH1 antagonists have been proposed as pharmacological treatment of such stress-related disorders. Here we show that the carbamoyl-1,2,3,6-tetr...

Wolfschoon-Pompo, A.K.ostermeyer, H1; Weiss, G., 1982: The NPN non protein nitrogen-fraction of cows milk. V. Analytical methods.1. Milchwissenschaft = Milk science international: 80-85