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Effects of nicotinamide and insulin on glycosylated hemoglobin and blood glucose in thyroidectomized streptozotocin-diabetic rats

, : Effects of nicotinamide and insulin on glycosylated hemoglobin and blood glucose in thyroidectomized streptozotocin-diabetic rats. Japanese Journal of Pharmacology 32(5): 903-907

The present study deals with the effects of nicotinamide and insulin on glycosylated hemoglobin (HbA1) and blood glucose in thyroidectomized streptozotocin (STZ)-diabetic male rats. Nicotinamide (500 mg/kg body wt., i.p.) significantly decreased the levels of HbA1 and blood glucose in both STZ-treated (65 mg/kg body wt., i.v.) intact and STZ-treated thyroidectomized animals. Administration of NPH-insulin recovered hyperglycemia, and the increased HbA1 in thyroidectomized STZ-diabetic rats to control levels.


PMID: 6217365

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Zendejas, B.; Cook, D.A.; Farley, D.R., 2011: Teaching first or teaching last: does the timing matter in simulation-based surgical scenarios?. The optimal timing of instruction in simulation-based scenarios remains unclear. We sought to determine how varying the timing of instruction, either before (teaching first) or after (teaching last) the simulation, affects knowledge outcomes of su...

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Muszyński, Z.; Kedzia, W.B., 1974: Production of extracellular substances by different virulent strains of Pseudomonas aeruginosa. Journal of Hygiene, Epidemiology, Microbiology, and Immunology 18(3): 313-315

Bank, N.; Su, W.S.; Aynedjian, H.S., 1978: A micropuncture study of HCO3 reabsorption by the hypertrophied proximal tubule. In rats with renal failure produced by excision of one kidney and infarction of large portions of the other kidney, given a low calcium, high phosphorus diet for 2-3 weeks, GFR was reduced by 80 percent, the fractional excretion of sodium increase...

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Timmons, G.D., 1979: Gerald D. Timmons, Ph.G., D.D.S., D.Sc., LL.D., F.A.C.D. August 9, 1897-July 22, 1978. Journal of Dental Education 43(2): 68-69

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Bernier B., 1968: Fertilization in natural coniferous forests of quebec. Fonds de Recherches Forestieres de l'Universite Laval Bulletin 12: 11-12

Gronow, J., 1990: Nepal: forest user groups: approaches to local forest management in the hills. In the 1980s, the Nepalese government adopted a forest policy which involved handing over the hill forests to 'user groups' or local organizations. This article traces the development of the Community Forestry Programme and argues that e...

Ashourian, N.; Mousdicas, N., 2006: Images in clinical medicine. Pellagra-like dermatitis. New England Journal of Medicine 354(15): 1614-1614