+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Effects of nifedipine and Bay-K-8644 on the release of catecholamines from the dog adrenal gland in response to splanchnic nerve stimulation

, : Effects of nifedipine and Bay-K-8644 on the release of catecholamines from the dog adrenal gland in response to splanchnic nerve stimulation. Clinical and Experimental Pharmacology & Physiology 20(1): 35-39

1. The effects of nifedipine and Bay-K-8644 on the release of adrenal catecholamines were examined in anaesthetized dogs. 2. Splanchnic nerve stimulation (SNS) at 1 and 3 Hz produced frequency-dependent increases in adrenaline (ADR) and noradrenaline (NA) output determined from adrenal venous blood. 3. Neither nifedipine (10 and 30 micrograms/kg, i.v.) nor Bay-K-8644 (10 and 30 micrograms/kg, i.v.) modified the SNS-induced increases in catecholamine output. Basal catecholamine output tended to be increased and decreased by nifedipine and Bay-K-8644, respectively. 4. Nifedipine produced significant decreases in arterial pressure and renal blood flow rate. Bay-K-8644 produced a significant increase in arterial pressure associated with a decrease in renal blood flow rate. 5. These results suggest that dihydropyridine-sensitive calcium channels do not play a major role in adrenal catecholamine release evoked by SNS.


PMID: 7679341

Other references

Krzempek, K.; Sotor, J.; Abramski, K., 2016: Compact all-fiber figure-9 dissipative soliton resonance mode-locked double-clad Er:Yb laser. NlmCategory="UNASSIGNED">The first demonstration of a compact all-fiber figure-9 double-clad erbium-ytterbium laser working in the dissipative soliton resonance (DSR) regime is presented. Mode-locking was achieved using a nonlinear am...

Walker L.I., 1985: Nucleolus organizer regions in 2 phyllotine rodent species and their experimental hybrids. Archivos de Biologia y Medicina Experimentales 18(1): R-74

Ellis, J.A.; Allan, G.; Krakowka, S., 2008: Effect of coinfection with genogroup 1 porcine torque teno virus on porcine circovirus type 2-associated postweaning multisystemic wasting syndrome in gnotobiotic pigs. Objective - To determine whether genogroup 1 porcine torque teno virus (g1-TTV) can potentiate clinical disease associated with porcine circovirus type 2 (PCV2). Sample population - 33 gnotobiotic baby pigs. Procedures - Pigs were allocated into 7...

Batiza R.; Hekinian R.; Bideau D.; Francheteau J., 1995: Chemistry of deep (3500-5600 m) Pacific MORB; why is the Pacific anomalous?. Geophysical Research Letters 22(22): 3067-3070

Zhao, Q.; Wang, S.; Kong, M.; Geng, W.; Li, R.K.Y.; Song, C.; Kong, D., 2012: Phase morphology, physical properties, and biodegradation behavior of novel PLA/PHBHHx blends. In this study, two biodegradable polyesters [i.e., polylactic acid (PLA) and poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx)] with complementarity in terms of mechanical performance have been combined, and a series of blends with a broad ra...

Ambrus J.L.; Ambrus C.M., 1968: Effect of steroids 17 alpha 19 northindrone hematol ethinyl estradiol hematol hydrocortisone hematol on the blood coagulation system woman abstract. Effect Of Steroids 17 Alpha-19 Northindrone Hematol Ethinyl Estradiol Hematol Hydrocortisone Hematol on The Blood Coagulation System Woman Abstract

Kröger, M.; Fels, G., 2006: Combined biological-chemical procedure for the mineralization of TNT. Contamination of ground and surface water with 2,4,6-trinitrotoluene (TNT) and its biological and chemical transformation products are a persisting problem at former TNT production sites. We have investigated the photochemical degradation of TNT a...

Rudan, V.; Tripković, M.; Vidas, M., 2003: The application of psychoanalytic principles to the study of "magic". In this paper Freud's work on animism and magic is elaborated. Those two subjects are presented mainly in his work "Totem and Taboo" (1913). The true motives, which lead primitive man to practice magic are, according to Freud, human...

Dodge, W.F.; West, E.F.; Travis, L.B., 1974: Bacteriuria in school children. Observations on outcome following detection in 110 girls. American Journal of Diseases of Children 127(3): 364-370

Rozenshtraukh L.V.; Kholopov A.V.; Yushmanova A.V., 1973: Suppression of atrial arrhythmia with myo cardial subthreshold electric stimuli activating intra cardiac nerves part 2 removal of arrhythmia conditioned by excitation circulation. Biofizika 18(5): 891-896