geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Effects of nitroglycerin and ethylene glycol dinitrate mixture (blasting oil) on rat brain, liver and kidney


, : Effects of nitroglycerin and ethylene glycol dinitrate mixture (blasting oil) on rat brain, liver and kidney. Research Communications in Chemical Pathology and Pharmacology 37(1): 113-121

Rats were injected intraperitoneally (150 mg/kg) with a mixture of nitroglycerin and ethylene glycol dinitrate (1:3). Treatment caused a transient small increase in methemoglobin contents in blood and diminished contents of reduced glutathione in liver and brain. Hepatic cytochrome P-450 concentration and ethoxycoumarin deethylase activity decreased shortly after exposure but later the effect disappeared. Succinate dehydrogenase activity decreased in liver, kidney and brain. In brain, activity of creatine kinase increased significantly and slight increase in hepatic UDPglucuronosyltransferase and epoxide hydrolase activity was observed. Renal ethoxycoumarin activity increased transiently. The results point to interaction of hydrolytically released nitrite with hemoproteins.

US$29.90

PMID: 6812185


Other references

Mochnacz, N.; Reist, J., 2007: Biological and habitat data for fish collected during stream surveys in the Deh Cho Region, Northwest Territories, 2006. Stre.am surveys were conducted in selected reaches of three streams in the Deh Cho Region during July, 2006. Streams were electrofished and habitat availability and use were recorded. A total of 223 fish representing eight different species were c...

Semina I.E.; Yankina Z.K., 1989: Use of immunoblotting techniques for the identification of individual proteins in bordetella pertussis antigenic complexes. The composition of antigenic complexes isolated from the supernatant fluid of B. pertussis culture has been studied by means of immunoblotting techniques. In preparations obtained from B. pertussis strains 305 and 475 fragments of the molecule of...

Patrocínio, A.Otávio.T.; Iha, N.Y.Murakami., 2008: Photoswitches and luminescent rigidity sensors based on fac-[Re(CO)3(Me4phen)(L)]+. The fac-[Re(CO)3(Me4phen)(trans-L)]+ complexes, Me4phen = 3,4,7,8-tetramethyl-1,10-phenanthroline and L = 4-styrylpyridine, stpy, or 1,2-bis(4-pyridyl)ethylene, bpe, were synthesized and characterized by their spectroscopic,photochemical, and phot...

Behrens, U.; Teubner, J.; Evertsz, C.J.G.; Walz, M.; Peitgen, H.J.ergens And Heinz Otto, 1996: Computer assisted dynamic evaluation of contrast-enhanced breast-MRI. Lemke, H U [Author], Vannier, M W [Author], Inamura, K [Author], Farman, A G [Author] International Congress Series; CAR '96: Computer assisted radiology 362-367

Wheeler W.E.; Noller C.H.; White J.L.; Hruska R.L., 1980: Influence of limestone source on the performance of beef steers fed corn silage corn grain based diets. Journal of Animal Science 51(SUPPL 1): 409

Cheston, J.H., 1951: The over-all problem in hospital finance. Modern Hospital 76(1): 82-86

Isola J., 1988: Analysis of steroid receptors by immunofluorescence and flow cytometry. Cytometry. 2: 49

Anonymous, 1980: Water-level monitoring and earthquakes from March 16 to May 31, 1980. Bulletin of the Hot Springs Research Institute, Kanagawa Prefecture = Kanagawa-Ken Onsen Kenkyujo Hokoku 12(1): 10-17

Yarger Harold L.; McCauley James R.; James Gerard W.; Magnuson Larry M.; Marzolf G.R.chard, 1973: Water turbidity detection using ERTS-1 imagery. Perry and Tuttle Creek reservoirs, Kansas.

Sindhu, R.; Kuttiraja, M.; Binod, P.; Preeti, V.Elizabeth.; Sandhya, S.Variem.; Vani, S.; Sukumaran, R.Kumar.; Pandey, A., 2012: Surfactant-assisted acid pretreatment of sugarcane tops for bioethanol production. Sugarcane tops is one of the largest biomass resources in India and in tropical countries such as Brazil in terms of surplus availability. Conversion of this feedstock to ethanol requires pretreatment to make it more accessible for the enzymes use...