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Effects of oral disopyramide phosphate on induction of paroxysmal supraventricular tachycardia


, : Effects of oral disopyramide phosphate on induction of paroxysmal supraventricular tachycardia. Circulation 64(1): 169-175

The effects of oral disopyramide phosphate on laboratory induction of paroxysmal supraventricular tachycardia (PSVT) were studied in 16 patients with clinical PSVT. After control electrophysiologic study to determine the inducibility and mechanism of PSVT, patients were given 200-300 mg (275 +/- 45 mg, mean +/- SD) of disopyramide for three to five doses over 24 hours and were then restudied. All patients had inducible, sustained PSVT during the control study. After disopyramide, PSVT was noninducible in eight patients (50%), including six of nine with atrioventricular nodal reentrance and two of seven with atrioventricular reentrance; inducible but nonsustained in two (12.5%) (both with atrioventricular reentrance); and inducible and sustained in six (37.5%). The benefit of disopyramide seemed predominantly to reflect depression of conduction in the retrograde limb of the circus movements, although effects upon the antegrade limb were also observed. In the eight patients with inducible PSVT before and after disopyramide, tachycardia cycle length increased from 348 +/- 33 to 404 +/- 29 msec (mean +/- SEM) (p less than 0.001). These results suggest that disopyramide would be effective in preventing recurrence of clinical PSVT in selected patients.

US$29.90

PMID: 7237716


Other references

West David P.J.; Lux Daniel R., 1989: Evidence for late Paleozoic-early Mesozoic extensional tectonism along the Norumbega fault zone, southwestern Maine. Abstracts with Programs - Geological Society of America 21(6): 141

Kim, J.Heon.; Song, Y.Seob., 2016: Current status of stem cell therapy in urology. Korean Journal of Urology 56(6): 409-411

Hull, D.A.; Stoeckinger, J.M.; McGee, E.M.; Hopkins, S.F.; Rogers, E.L., 1985: Lord's rectal dilitation and treatment of rectal disease. Journal of the Kentucky Medical Association 83(5): 242-246

Perk, J.; Hambraeus, K.; Burell, G.; Carlsson, R.; Johansson, P.; Lisspers, J., 2015: Study of Patient Information after percutaneous Coronary Intervention (SPICI): should prevention programmes become more effective?. This cross-sectional observational study was designed to evaluate the uptake and outcome of patient education after percutaneous coronary intervention (PCI). A questionnaire containing 41 items was handed out to consecutive patients from randomly...

Nkenke, E.; Kramer, M.; Benz, M.; Maier, T.; Wiltfang, J.; Haeusler, G.; Neukam, F.W., 2003: Application of optical 3D imaging in exophthalmometry. Lemke, Heinz U [Editor, Reprint Author], Vannier, Michael W [Editor], Inamura, Kiyonari [Editor], Farman, Allan G [Editor], Doi, Kunio [Editor], Reiber, John H C [Editor] Computer assisted radiology and surgery : 1407

Sohl, T.L.; Sleeter, B.M., 2012: Land-use and land-cover scenarios and spatial modeling at the regional scale. Land-use and land-cover (LULC) change has altered a large part of the earth's surface. Scenarios of potential future LULC change are required in order to better manage potential impacts on biodiversity, carbon fluxes, climate change, hydrolog...

Gianoulakis, C.; De-Waele, J.-Pascal, 1994: Genetics of alcoholism: Role of the endogenous opioid system. At the present time alcoholism is recognized as a metabolic disease exhibiting the clinical features of craving for alcohol, loss of control over drinking, tolerance and physical dependence on alcohol, while both epidemiological and experimental s...

Banks, W.A., 2009: Characteristics of compounds that cross the blood-brain barrier. Substances cross the blood-brain barrier (BBB) by a variety of mechanisms. These include transmembrane diffusion, saturable transporters, adsorptive endocytosis, and the extracellular pathways. Here, we focus on the chief characteristics of two me...

Paul, M.; Hermann, K.; Printz, M.; Lang, R.E.; Unger, T.; Ganten, D., 1983: The brain angiotensin system: subcellular localization and interferences with converting enzyme inhibitors. Renin is stored in synaptosomes of rat brain, separately from cathepsin D and intraneuronal angiotensin II (ANG II) has been demonstrated with the electron-microscope. Although the subcellular localization of other components of the renin-angioten...

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