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Identification of a unique mammalian species of cholyl-CoA: amino acid N-acyltransferase


, : Identification of a unique mammalian species of cholyl-CoA: amino acid N-acyltransferase. Biochimica et Biophysica Acta 665(3): 612-614

The N-acyltransferase enzyme which catalyzes the conjugation of the CoA adducts of bile acids with amino acid has been partially purified from dog liver. Unlike the N-acyltransferase from five other mammalian species, the enzyme from dog liver was unable to synthesize glycine conjugates from cholyl-CoA in vitro even in the presence of 0.1 M glycine. The enzyme did catalyse the synthesis of taurine conjugates. Thus, the enzyme from dog liver resembles non-mammalian forms of the enzyme which also synthesize only taurine conjugates. However, the molecular weight of the enzyme from dog liver was found to be approximately 45 700, which is similar to values reported for other mammalian forms and considerably smaller than the molecular weight of 65 000 reported previously for a non-mammalian form of the enzyme.

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PMID: 7295754


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DeVore, C.H.; Beck, F.M.; Clark, P.M.; Goorey, N.J., 1989: Cognitive style as related to emotional empathy. This study examined relationships among two measures of FDI (the hidden figure test (HFT) and the portable rod and frame test (PRFT) and a measure of interpersonal sensitivity (the questionnaire measure of emotional empathy (QMEE] in a group of de...

Smith, C.U.M.Chris., 2012: NeurHistAlert 16. Journal of the History of the Neurosciences 21(3): 319-326

Levä, S., 1969: Scandinavian observations concerning nursing education. Sairaanhoitaja. Sjukskoterskan 45(2): 70-72

Arnold, S.; Plate, U.; Weismann, H.-Peter; Kohl, H.; Hoehling, H.-Juergen, 1997: Quantitative electron-spectroscopic diffraction (ESD) and electron-spectroscopic imaging (ESI) analyses of dentine mineralisation in rat incisors. Primary crystal formations in all hard tissues are, according to our investigations, Ca-phosphate chains composed of nanometer sized particles (dots) which develop along the matrix macromolecules. In circumpulpal dentine the centre-to-centre dista...

Praud, E., 1971: Accidents resulting from corticotherapy. Soins; la Revue de Reference Infirmiere 16(8): 371-376

Bouwsma O.; Zappa U.; Polson A., 1988: Osteoclast proliferation in alveolar bone after metronidazole administration. Journal of Dental Research 67(SPEC ISSUE MAR): 208

Van Der E.A.J., 1985: The pharmacology of 5 deoxy 5 fluorouridine relationship between antitumor activity and t 24 ras. Anticancer Research: 586

Younan, M.; Ali, Z.; Muller, W.; Bornstein, S., 2000: Streptococcus agalactiae infection in camels (Camelus dromedarius) in Kenya. Subclinical mastitis in camels due to Streptococcus agalactiae (Lancefield type B) was studied in different camel management systems in Kenya (Somali, Pokot, ranch-camels). S. agalactiae was found in udder infections in 6 out of 9 herds from which...

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