+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Inhibition of vitamin D2-induced arteriosclerosis in rats by depletion of complement with cobra venom factor

, : Inhibition of vitamin D2-induced arteriosclerosis in rats by depletion of complement with cobra venom factor. Artery 7(2): 109-122

Widespread calcerous deposits developed in the aorta, heart and kidneys of rats fed for 4 days with purina chow and high doses of vitamin D2 (200,000 IU/kg body wt/day). Decomplementation of rats with highly purified cobra venom factor (CoF) prior to vitamin D2 feeding, almost completely prevented calcium deposition in the aorta and arteritis. The mortality rate in the CoF-treated vitamin D2-fed rats was much lower than in untreated rats. These findings suggest that the complement system may be recruited in the pathogenesis of vitamin D2-induced arteriosclerosis.


PMID: 7000037

Other references

Patki, P.; Hamid, R.; Shah, P.J.R.; Craggs, M., 2005: Long-term efficacy of AMS 800 artificial urinary sphincter in male patients with urodynamic stress incontinence due to spinal cord lesion. Study design: Retrospective analysis.Objectives: To evaluate long-term efficacy and complications of AMS 800 ( American Medical Systems (R)) artificial urinary sphincter (AUS) in treatment of urodynamic stress incontinence (USI) in male patients w...

Salgado, G.F.; Alves, I.D.; Salamon, Z.; Hruby, V.J.; Tollin, G.; Brown, M.F., 2003: Activation of the GPCR prototype rhodopsin studied by plasmon-waveguide resonance spectroscopy. Biophysical Journal 84(2 Part 2): 521a, February

Hunter, I.; Croxall, JP.; Prince, PA., 1982: The distribution and abundance of burrowing seabirds (Procellariiformes) at Bird Island, South Georgia: 1. Introduction and methods. The habitats utilized by burrowing petrels at Bird Island, South Georgia, are described and the habitat modification induced by the activities of fur seals and other seabirds summarized. The field methods for an investigation of the distribution a...

Pulli, S.; Tesar, M., 1975: Phytophthora root rot in seeding-year alfalfa as affected by management practices inducing stress. Crop science: 15 (6) 861-864

Hammami, H.; Scouras, J.; Streiff, E.B., 1972: Congenital cataracts. Surgical results and statistical study of more than 25 years (1944-1971). Ophthalmologica. Journal International D'ophtalmologie. International Journal of Ophthalmology. Zeitschrift für Augenheilkunde 165(3-4): 208-211

Black R.A.; Smithson Scott B., 1988: Interpretation of bright reflection events within Long Valley Caldera utilizing a new probabilistic migration algorithm. Eos, Transactions, American Geophysical Union 69(44): 1327

Csillag, J.; Lukacs, A.; Osztoics, E.; Csatho, P.; Baczo, G., 2006: Trace metal concentrations in the liquid phase of phosphate rock-treated soils. Concentrations of potentially toxic elements (As, Ba, Cd, Co, Cr, Cu, Hg, Mn, Mo, Ni, Pb, Sr and Zn) were determined in the soil solution of two soils (acidic sandy and slightly acidic clay loam) treated with phosphate rocks having high Cd content...

Fejer, S.O., 1971: Selection of timothy (Phleum pratense L.) under different conditions of culture. Two generations of recurrent selection for herbage weight under different conditions of competition and cutting frequency between hexa-ploid cultivars and within their open-pollinated progenies was inefficient in producing an improvement over the...

Anonymous, 2009: Women's health in rural China. Lancet 374(9687): 358-358

Swift, E.J.; Triolo, P.T.; Barkmeier, W.W.; Bird, J.L.; Bounds, S.J., 1996: Effect of low-viscosity resins on the performance of dental adhesives. To determine whether the use of low-viscosity intermediate resins (LVR) reduces microleakage of dental adhesive systems. Wedge-shaped Class V cavities were prepared in sound extracted molars. Occlusal margins were in enamel and gingival margins we...