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Nodular regenerative hyperplasia of the liver associated with progressive systemic sclerosis: a case report with ultrastructural observation

, : Nodular regenerative hyperplasia of the liver associated with progressive systemic sclerosis: a case report with ultrastructural observation. Journal of Rheumatology 10(5): 748-752

We present a case of nodular regenerative hyperplasia of the liver in association with progressive systemic sclerosis, the third such association in the literature. Clinically, there was elevation of liver function tests, and no varices were found at autopsy. Ultrastructural examination of the liver showed deposition of abnormal material in arterioles, capillaries, and sinusoids. We postulate that these ultrastructural alterations could account for the clinical and pathological findings commonly seen in nodular regenerative hyperplasia of the liver.


PMID: 6644697

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