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Parathyroid hormone responses to the dopaminergic agonist 2-amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene

, : Parathyroid hormone responses to the dopaminergic agonist 2-amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene. Life Sciences 35(14): 1469-1474

Plasma parathyroid hormone (PTH) responses to the dopaminergic agonist 2-amino-6,7-(OH)2-1,2,3,4-tetrahydronaphthalene (ADTN) have been studied in cattle. During ADTN infusions PTH increased within min in a dose-dependent manner, while calcium remained unchanged. Prolonged administration of ADTN caused transient PTH responses and crosstachyphylaxis to the subsequent administration of the beta-adrenergic agonist isoproterenol, but not to hypocalcemia, caused by infusions of ethylene-glycol-bis (beta-aminoethylether)-N,N'-tetraacetate. PTH responses were not modified by the beta-adrenergic blocking agent propranolol, infused in amounts earlier shown to suppress PTH responses to isoproterenol and epinephrine. In conclusion, the dopaminergic agonist ADTN caused a direct and transient stimulation of PTH secretion, not mediated by hypocalcemia or by beta-adrenergic receptors on parathyroid cells. However, crosstachyphylaxis to isoproterenol, but not to hypocalcemia, was observed.


PMID: 6482667

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Zollikofer, G., 1942: Der Gehalt an Aminosaurenstickstoff in genussreifen Kasen. Determinations were made for total N, soluble N, and amino N in the soluble fraction in about 50 vars. of ripened cheese. The soluble N and amino N were calculated as % of the total N. Wide variations were found in soluble and amino N between diff...

Quiggin, J., 1992: How to set catch quotas: a note on the superiority of constant effort rules. Journal of environmental economics and management 22(2): 199-203

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