+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Peripheral nerve conduction function in patients treated with antituberculotic agents, with special reference to ethambutol and isoniazid

, : Peripheral nerve conduction function in patients treated with antituberculotic agents, with special reference to ethambutol and isoniazid. Folia Psychiatrica et Neurologica Japonica 34(1): 57-64

The electrophysiological examination was made to clarify the effect of ethambutol on the peripheral nervous system in 39 patients at tuberculous sanatorium. Abnormalities in the sensory nerve action potential (toe-ankle) were observed in about 10 percent of the patients treated with ethambutol, and these patients were mostly elderly and/or received the high dose of ethambutol. The mixed nerve conduction velocity (ankle-knee) showed a significant decrease compared with healthy subjects. The conduction velocity tended to decrease in the high ethambutol dosage (200 gm or more) group compared with the low dosage (200 gm or less) group. The tendency for the conduction velocity to decrease was also observed in the 18 patients treated with isoniazid but the abnormalities were mild compared with the ethambutol.


PMID: 6248441

Other references

Martos, A.; Raso, A.; Jiménez, M.; Petrášek, Zěk.; Rivas, Gán.; Schwille, P., 2016: FtsZ Polymers Tethered to the Membrane by ZipA Are Susceptible to Spatial Regulation by Min Waves. Bacterial cell division is driven by an FtsZ ring in which the FtsZ protein localizes at mid-cell and recruits other proteins, forming a divisome. In Escherichia coli, the first molecular assembly of the divisome, the proto-ring, is formed by the...

Wu, L.; Zhang, C.; Tian, Z.; Zhang, J., 2011: NK cell-based approach for screening novel functional immune genes. The human genome project provides extensive opportunities for the discovery of novel functional immune genes. In order to find innate immune genes that might regulate the function of NK cells from a cDNA library, we used an NK cell line, NK-92, as...

Edwards, R., 1964: Comparison Of Scarification And Injection Methods Of Bcg Vaccination. Revue D'hygiene et de Medecine Sociale 17: 239-241

Adams K.M., 1990: Subcortical dementias aids and the nld syndrome. Journal of Clinical & Experimental Neuropsychology 12(1): 28

Hattyasy, D., 1968: On the physiological elimination of the nerves of the deciduous dental pulp. Deutsche Zahnarztliche Zeitschrift 23(10): 984-990

Carteaux, G.; de Prost, N.; Razazi, K.; Mekontso Dessap, A., 2016: The authors reply. Critical Care Medicine 44(11): E1154-E1154

Sakaki, N.; Kozawa, H.; Sanaka, M.; E.A., 2002: Improvement of atrophic gastritis after Helicobacter pylori eradication therapy. Improvement of atrophic gastritis after Helicobacter pylori (H. pylori) eradication therapy was investigated by endoscopic follow-up study with histological assessment, using biopsy specimens. From our preliminary analysis, it was revealed that th...

Inmaculada, N-González.; Francisco, Gía-Carmona., 2016: Characterization of cross-linked immobilized arylesterase from Gluconobacter oxydans 621H with activity toward cephalosporin C and 7-aminocephalosporanic acid. Cross-linked enzyme aggregates (CLEAs) were prepared from several precipitant agents using glutaraldehyde as a cross-linking agent with and without BSA, finally choosing a 40% saturation of ammonium sulfate and 25 mM of glutaraldehyde. The CLEAs o...

Plintovic, V.; Scholtz, J., 1970: Occurrence of gonorrhea in our material during the past 10 years. Ceskoslovenska Gynekologie 35(5): 269-271

Sottani, C.; Poggi, G.; Melchiorre, F.; Montagna, B.; Minoia, C., 2013: Simultaneous measurement of doxorubicin and reduced metabolite doxorubicinol by UHPLC-MS/MS in human plasma of HCC patients treated with TACE. A sensitive, selective, accurate and precise method for simultaneous quantification of doxorubicin (DOX) and doxorubicinol (DOXol) in human plasma of patients diagnosed as having intermediate stage unresectable hepatocellular carcinoma (HCC) was d...