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Phenethyl alcohol as a suppressor of the envA phenotype associated with the envA gene in Escherichia coli K-12

, : Phenethyl alcohol as a suppressor of the envA phenotype associated with the envA gene in Escherichia coli K-12. Journal of Bacteriology 108(1): 51-58

In Escherichia coli K-12 the envA gene was previously shown to mediate chain formation and a decreased tolerance to several antibacterial agents. Phenethyl alcohol at low concentrations has now been found to increase the tolerance to actinomycin D, ampicillin, rifampin, and gentian violet in strains containing envA. The increased tolerance to gentian violet was correlated to a decreased uptake of the dye. A phenotype suppression of chain formation and colony morphology in envA mutants was also obtained. Except for an increase in palmitic acid, chemical analysis revealed no differences between an envA and its wild-type strain in the lipopolysaccharide part of the envelope. However, a decrease in the amount of phosphatidylglycerol and a C18: 1 fatty acid was observed in the extractable lipids of a strain containing envA. Growth in the presence of phenethyl alcohol reversed the changes in fatty acid and the phospholipid composition. Phenethyl alcohol was found to cause an immediate but transient inhibition of ribonucleic acid synthesis. It is suggested that this inhibition affects the penetrability barrier of the outer cell envelope layers in strains containing envA.


PMID: 4941568

Other references

Lagace, J.; Beaulac, C.; Clement Major, S., 1997: Therapeutic liposomal formulation. Official Gazette of the United States Patent & Trademark Office Patents 1202(1): 364, Sept 2

Khan, A.G.; Saif, S.R., 1973: Some observations on mycorrhizae of Olea cuspidata Wall. Mycorrhizas were found on O. cuspidata from the foothills of the Himalayas, ecto- and endomycorrhiza occurring on different roots of the same plant. The significance of these findings for olive cultivation is discussed.

Robinson P.H.; Tamminga S.; Van Vuuren A.M., 1987: Influence of declining level of feed intake and varying the proportion of starch in the concentrate on rumen ingesta quantity composition and kinetics of ingesta turnover in dairy cows. Five dairy cows fitted with large-diameter rumen cannulae were fed diets of two-thirds pelleted concentrate that contained 5 proportions of starch (8, 14, 20, 26 or 32%). Measurements were made over one complete lactation to determine the effects...

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