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Preoperative chemotherapy of squamous cell carcinoma of the head and neck with V-T-M schedule

, : Preoperative chemotherapy of squamous cell carcinoma of the head and neck with V-T-M schedule. Laryngologie, Rhinologie, Otologie 60(5): 271-274

13 patients with far advanced squamous cell carcinoma of the head and neck were treated with a low dose combination chemotherapy of Vincristine, Bleomycin and Methrotrexate during 7--8 weeks prior to surgery or radio-therapy. V-B-M was given as an out- patient regimen. 9 patients were treated the first time ever, 4 patients suffered of tumor-recurrence. 5 patients i.e. 38% achieved complete remission of all measurable disease, a total of 9 patients i.e. 69% achieved a partial remission of more than 50%. Prior treatment or localisation of tumor did not influence the results. Competent application warranted, toxicity was mild. The significance of pre-operatively achieved complete remission is discussed. Short-term follow up does not yet permit any statement upon survival.


PMID: 6164894

Other references

Mazur, A.F., 1989: Organizational characteristics of supplying medical stores under extreme situations. Voenno-Meditsinskii Zhurnal: 15-17

Sacks, W., 1995: Molecular characterization of nucleotide sequences encoding the extracellular glycoprotein elicitor from Phytophthora megasperma. CDNA sequences encoding the 42 kDa glycoprotein elicitor from the oomycete, Phytophthora megasperma, that induces the defense response in parsley have been cloned and sequenced. The 5' end of the mRNA matches a consensus derived from sequence...

Yankina V.P.; Yashchak T.V., 1970: Information for establishing the maximum allowable concentration of the dye acid violet s. Tr Permsk Med Inst 82: 151-156

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O'Grady, Damian, 2008: First-order morphology of modern clastic deep-water systems. On passive margins the continental slope is dominantly shaped by erosion and deposition from sediment gravity flows rather than tectonic movements. Sediment gravity flows respond to existing sea-floor gradients but also modify gradient through suc...

Samani, N.; Gohari-Moghadam, M.; Safavi, A.A., 2007: A simple neural network model for the determination of aquifer parameters. A simple artificial neural network (ANN) model is developed for the determination of non-leaky confined aquifer parameters by normalizing and applying the principal component analysis (PCA) on adopted training data pattern from Lin and Chen [Lin,...

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D.F.rteza, R.; Li, D.Q.; Mckenzie, J.M.; Zakarija, M., 1993: An intracellular calcium pool necessary for the action of interferon-gamma on FRTL5 cells. De Bellis, A [Editor], Marschke, K B [Editor] Serono Symposia Publications from Raven Press; New perspectives in endocrinology : 111-114

Walsh, M.P., 1981: Calmodulin-dependent myosin light chain kinases. Cell Calcium 2(4): 333-352

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