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Prospective trial of operative versus non-operative treatment of severe vesicoureteric reflux: two years' observation in 96 children


, : Prospective trial of operative versus non-operative treatment of severe vesicoureteric reflux: two years' observation in 96 children. British Medical Journal 287(6386): 171-174

Children with severe vesicoureteric reflux were allocated at random within three age groups (less than 1, 1-5, and greater than or equal to 6 years) to either operative or non-operative treatment. In 96 children who completed two years' observation there was no significant difference between treatment groups in either the incidence of breakthrough urinary tract infection, slope clearance of 51Cr-edetic acid, renal length, new scar formation, or progression of existing scars. Ureteric reimplantation was technically successful in 97% of cases, whereas 74% of ureters managed non-operatively still showed significant reflux at two years. No short term advantage was shown for either form of treatment in this series, but the long term effects of persistent, severe vesicoureteric reflux require further study. The prevention of reflux nephropathy probably demands the identification of vesicoureteric reflux before the advent of urinary tract infection, a goal not attainable with present invasive techniques.

US$29.90

PMID: 6409239


Other references

McMillan, T., 2002: Will to live?. New Scientist 165(2220): 50-51

Rauch, J., 1990: Naturschutz in einem stark besuchten FDGB-Erholungsheim bei Rheinsberg. Falke, 375: 164-166

Cummins D.I.; Elderfield H., 1994: The strontium isotopic composition of Brigantian (late Dinantian) seawater. Strontium isotopic determinations of different fossiliferous biominerals from Brigantian (= late Dinantian) carbonates in northern England reveal that many are affected by diagenetic overprinting of their original (super 87) Sr/ (super 86) Sr rati...

Sheĭkh-Zade, I.R.; Kubantsev, A.V.; Galenko-Iaroshevskiĭ, P.A., 1988: A method of modelling myocardial fibrillation. A method of controlled atrial fibrillation modelling including the paired stimulation of the right atrium induced by using a transvenous bipolar catheter during vagal arrest of the heart is presented. The myocardial fibrillation is supposed to res...

Govallo V.I.; Golodnenkova V.N.; Rudenko T.G., 1966: Utilization of hetero specific anti lymphocyte serum in skin grafts. Anon Transplantatsiya Organov I Tkanei (Transplantation Of Organs And Tissues ) Meditsina: Moscow, Ussr, From Ref Zh 1967 No 8 53 398-399

Nardi, N.Beyer.; Camassola, M., 2011: Isolation and culture of rodent bone marrow-derived multipotent mesenchymal stromal cells. Initial attempts to cultivate mesenchymal stem cells (MSCs) were more successful from human than murine tissues. Methods for the in vitro expansion of murine MSCs were described more recently, but are now well established. Despite limitations such...

Lagoe, R.J., 1987: Hospital stays by diagnosis related group for neurologic patients treated medically. We analyzed differences in hospital stays by diagnosis related group for neurologic patients treated medically in Sacramento, CA, and Syracuse, NY, between 1981 and 1984. Differences between stays were highest for DRGs with large proportions of el...

WangHaiYan; XuYan; FanLi; JinYaoGuang, 2008: Enzymatic characteristics of alcohol acetyltransferase from Hanseniaspora valbyensis, a non-Saccharomyces yeast. Alcohol acetyltransferase (AAT) catalyzing 2-phenylethyl alcohol and acetyl co-enzyme A (acetyl-CoA) to form phenylethyl acetate in <i>Hanseniaspora valbyensis</i> was studied. The enzyme was solubilized from lipid particles using 1% T...

Williamson, J.; Darnell, R.; Krewer, G.N.smith, S., 1996: Gibberellic acid (GA3) sprays increase fruit set and yield of rabbiteye blueberries. Proceedings of the annual meeting of the Florida State Horticultural Society09(109): 212-214

Smalling, R., 1996: In the same vein--a step backwards. Catheterization and Cardiovascular Diagnosis 38(2): 171-171