+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Role of brain dopaminergic mechanisms in rodent aggressive behavior: influence of (+/-)N-n-propyl-norapomorphine on three experimental models

, : Role of brain dopaminergic mechanisms in rodent aggressive behavior: influence of (+/-)N-n-propyl-norapomorphine on three experimental models. Psychopharmacology 70(1): 63-68

(+/-)N-n-Propyl-norapomorphine (NPA), a potent agonist of brain dopamine receptors, influences aggressive behavior, but the type of influence depends on the experimental conditions. In rats, NPA increases aggression elicited by electrical foot shock, but decreases predatory aggression against turtles as well as isolation-induced aggression in male mice. NPA proves more potent than apomorphine in both the foot shock and predatory test. A per se ineffective dose of haloperidol (0.05 mg/kg-1 IP) antagonizes NPA in the rat foot shock test as well as in the isolated male mouse test. The relevance of stereotyped movements for NPA influence on aggressive behavior is briefly discussed.


PMID: 6775337

Other references

Gobbi, P.G.; Crema, A.; Cambiè, G.; Rossi, M.; Chériè Lignière, E.L., 1984: Double successive pulmonary and cardiac thromboembolic manifestations in a case of undifferentiated carcinoma of the adrenal glands. Recenti Progressi in Medicina 75(1): 39-44

Pinto, D.J., 1968: Jejunal diverticula in the presence of small-bowel obstruction. British Journal of Surgery 55(4): 264-265

Escobales, N.; Rivera Correa, M.; Altieri, P.I.; Rodriguez, J.F., 1999: Relationship between the synthesis of nitric oxide and arginine transport in vascular smooth muscle cells. FASEB Journal 13(4 PART 1): A438, March 12

Jones, L.T., 1975: Trials and tribulations of an ophthalmic anatomist. Transactions of the Pacific Coast Oto-Ophthalmological Society Annual Meeting 56: 11-16

Cai, J.; Limke, T.L.; Ginis, I.; Rao, M.S., 2003: Identifying and tracking neural stem cells. Hematopoietic stem cells, unlike neural stem cells, can be readily identified and isolated from developing and adult cell populations using positive and negative selection criteria. Isolating stem cells and progenitor cells from neural tissue has...

Trouillas, P.; Betuel, H., 1977: Hypocomplementaemic and normocomplementaemic multiple sclerosis. Genetic determinism and association with specific HLA determinants (B18 and B7). Seventy-five patients with multiple sclerosis (MS) were treated for complement components C3, after factor B, C4, and tested for HLA-A and B-determinants. Levels of IgG, IgA, IgD, IgE and titres of measles antibodies were also determined. Correlat...

McCue, J.D., 1983: A febrile dairy farmer with nausea and diarrhea. Hospital Practice 18(6): 175, 180, 182-175, 180, 182

Silverthorne, M.C., 1959: Staphylococcal bacteremia and osteomyelitis successfully treated with novobiocin. A.M.A. Archives of Internal Medicine 103(1): 133-139

Hagemann, R., 1968: Cytogenetic analysis of somatic conversion in the tomato. Genetic studies have demonstrated "somatic allele-induced instability" at the sulf locus in Lycopersicon esculentum. The sulf locus lies close to, or within, the heterochromatic region of chromosome 2 and it is suggested that the somatic...

Zdeblick, T.A., 1998: Laparoscopic spinal fusion. This article details the development of the laparoscopic technique of interbody spinal fusion. The rationale for this procedure is discussed as are indications, contraindications, and operative technique. The results of over 100 laparoscopic lumba...