geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Selected ion monitoring of apomorphine in whole rat brain


, : Selected ion monitoring of apomorphine in whole rat brain. Journal of Chromatography 229(1): 95-102

Mass fragmentography was used for quantitation of apomorphine in whole rat brain. Following extraction with 0.45 N perchloric acid, the components were derivatized to the O,O-bis(trimethylsilyl) (TMS) derivatives with N,O-bis(trimethylsilyl)trifluoroacetamide at 30 degrees C. The molecular ions of the TMS derivatives of apomorphine (m/z 411) and N-n-propylnorapomorphine (m/z 439), as an internal standard, were assayed simultaneously by selected ion monitoring. Total chromatography time is 5 min. By this method 50 ng/ml can be determined with a coefficient of variation of 12.0%. Application of the method to apomorphine disposition study in whole rat brain was demonstrated.

US$29.90

PMID: 7085837


Other references

Lewis, H.L., 1975: Separate collective bargaining. Modern Healthcare 4(1): 51,53-4

Ledvina, M., 1988: Role of elastase and elastase-like enzymes in the pathogenesis of some diseases. Sbornik Vedeckych Praci Lekarske Fakulty Karlovy University V Hradci Kralove 31(5): 455-472

Walinder, J.; Thuwe, I., 1976: A law concerning sex reassignment of transsexuals in Sweden. In 1972, a law regulating surgical and legal measures reguired for sex reassignment came into force in Sweden. The law, its practical application, and the number of transsexual cases dealt with by the National Board of Health and Welfare during th...

Chudeau, R., 1909: Mission en Mauritanie Occidentale II Partie Geologique. Actes de la Societe Linneenne de Bordeaux, 63 51-71

Nilsen, S.P.; Chan, Y-Bun.; Huber, R.; Kravitz, E.A., 2004: Gender-selective patterns of aggressive behavior in Drosophila melanogaster. Complex behaviors, such as aggression, are comprised of distinct stereospecific behavioral patterns (modules). How such patterns get wired into nervous systems remains unknown. Recently, we reported on a quantitative analysis of fighting behavior...

Haist, V.; Seehusen, F.; Moser, I.; Hotzel, H.; Deschl, U.; Baumgärtner, W.; Wohlsein, P., 2008: Mycobacterium avium subsp. hominissuis infection in 2 pet dogs, Germany. Emerging Infectious Diseases 14(6): 988-990

Andrews A.F.; Bartlett R.H.; Roloff D.W., 1982: Mortality risk graphs for neo nates with respiratory distress. Pediatric Research 16(4 PART 2): 275A

Wang, H.; Wang, X.; Xu, X.; Lin, G., 2010: Mean corpuscular volume predicts prognosis in MDS patients with abnormal karyotypes. The prognostic value of karyotype in patients with myelodysplastic syndrome (MDS) is generally appreciated. However, the factors that are predictive of prognosis of patients with abnormal karyotypes are not known. In this study, we evaluated the p...

Imondi, R.; Zhu, Q.; Runko, E.; Yung, S.Y.; Kaprielian, Z., 1997: The tetraspan family member CO-029 is specifically expressed by peripheral neurons in the rat nervous system. Society for Neuroscience Abstracts 23(1-2): 1990

Sezer, O.; Gebesoglu, I.; Yuan, B.; Karaca, E.; Gokce, E.; Gunes, S., 2015: Fibular aplasia, tibial campomelia, and oligosyndactyly: a further patient with a 2-year follow-up. Clinical Dysmorphology 23(4): 121-126