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T-lymphocyte subsets in pleural fluids: discrimination according to traditional and monoclonal antibody-defined markers

, : T-lymphocyte subsets in pleural fluids: discrimination according to traditional and monoclonal antibody-defined markers. European Journal of Respiratory Diseases 65(8): 586-591

T-lymphocyte subpopulations in pleural fluid and in peripheral blood from 17 patients admitted for pleural effusion were identified by E-rosette formation and delineated by monoclonal antibodies OKT3 (peripheral T-cells), OKT4 (helper/inducer cells), and OKT8 (suppressor/cytotoxic cells). We studied 13 patients with specified pleural diseases (tuberculosis, malignancies, connective tissue diseases, congestive heart failure) and 4 patients with non-specified pleural diseases. Our findings showed that the percentage of T-cells increases in pleural fluid versus peripheral blood whatever the diagnosis is, and that these T-cells are predominantly helper/inducer cells. Moreover, a recently described T-lymphocyte subpopulation, which expresses neither T3 nor other monoclonal antibody-defined markers, seems to be concentrated in the pleural fluid, especially in tuberculosis and malignant effusions. Although T-lymphocyte delineation seems to fail to aid in etiological diagnosis of pleurisy, such determinations could provide informations about local pathogenic mechanisms.


PMID: 6240409

Other references

Morrow, E.M.; Smoller, J.W., 2006: The interface of genetics and clinical psychiatry. Introduction. Harvard Review of Psychiatry 14(2): 45-46

Christensen, S.; Jensen, S.E.; Lundbaek, K., 1955: The incorporation of P32 in phospholipid fractions in man; a preliminary report. Scandinavian Journal of Clinical and Laboratory Investigation 7(3): 212-217

Folkow, B., 1959: The efferent innervation of the cardiovascular system. Verhandlungen der Deutschen Gesellschaft für Kreislaufforschung 25: 84-96

Manz M.; Pfitzner P.; Luederitz B., 1989: Cibenzoline electrophysiologic effects in patients with supraventricular tachycardia. European Heart Journal 10(ABSTR SUPPL): 302

Yusuf, A.T.agi, R.; Malik, S., 2001: Somatic embryogenesis and plantlet regeneration from leaf segments of Piper colubrinum. Direct somatic embryogenesis from in vitro-cultured leaf segments of multiple disease-resistant pepper, Piper colubrinum Link is reported. Somatic embryos were initiated on Murashige and Skoog's (1962) basal medium containing 2.2 micromolar b...

Garel, D.; Wood, C.; Pariente, D.; Dommergues, J.P., 1989: Portal system obstruction of delayed onset following neonatal Staphylococcus aureus infection. Two neonates underwent staphylococcal septicemia with multiple intrahepatic abscesses, following umbilical catheterization in one case and due to superinfected heel puncture in the other case. At the first examination, liver ultrasonography showed...

Klausnitzer, B., 1975: Zur Kenntnis der Gattung Helodes Latr. (Col., Helodidae). (16. Beitrag zur Kenntnis der Helodidae). 7. Fortsetzung. Entomologische Nachrichten Dresden, 185: 73-78

Gratale, M.D.; Yunker, P.J.; Chen, K.; Still, T.; Aptowicz, K.B.; Yodh, A.G., 2014: Phonons in two-dimensional colloidal crystals with bond-strength disorder. We study phonon modes in two-dimensional colloidal crystals composed of soft microgel particles with hard polystyrene particle dopants distributed randomly on the triangular lattice. This experimental approach produces close-packed lattices of sph...

Timmis A.D.; Bojanowski L.M.R.; Najm Y.; Gosling R., 1987: Skeletal muscle perfusion in ccf the effects of captopril. Journal of the American College of Cardiology 9(2 SUPPL A): 202A

Bakke O.; Mostad A., 1980: The structure and conformation of tryptophan in the crystal of the pure racemic compound and the hydrogen oxalate. The crystal structure of pure DL-trytophan was determined by X-ray crystallographic methods using 522 reflections observed by counter methods. The crystals are monoclinic, space group P21/c with unit cell dimensions a = 18.986(8) .ANG., b = 5.768(...