geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

The Yentl syndrome in childhood asthma: risk factors for undertreatment in Swiss children


, : The Yentl syndrome in childhood asthma: risk factors for undertreatment in Swiss children. Pediatric Pulmonology 19(3): 156-160

Recent prevalence data for childhood asthma in Switzerland suggest a substantial underdiagnosis which seems to be more pronounced in girls. We further analysed our data trying to specify risk factors for underdiagnosis and undertreatment. Our special interest was focused on female sex as there is evidence for a sex-dependent diagnosis and treatment of chronic disease in adults, called the Yentl syndrome. The data are derived from a parent completed questionnaire survey of a stratified cluster sample of schoolchildren aged 7, 12, and 15 years. Besides the 12 months prevalence of asthma symptoms and bronchodilator treatment, the lifetime prevalence of an asthma diagnosis was noted. With a response rate of 97%, a total of 4353 completed questionnaires were analysed. While age was not associated with undertreatment (except for exercise-induced symptoms in adolescents), the lack of a formal diagnosis of asthma and atypical asthma symptoms other than wheeze such as chronic night cough were confirmed as significant risk factors for undertreatment. Of all boys reporting asthma symptoms 31% received bronchodilator treatment compared with only 15% of the symptom-reporting girls (P < 0.001). For all particular asthma-related symptoms (except wheeze), significantly more boys than girls (approximately double) received treatment. The physiological and psychological bases for these findings are discussed and suggest that gender is an important risk factor for underdiagnosis and undertreatment of asthma. Our research indicates that the Yentl syndrome may exist for childhood asthma.

US$29.90

PMID: 7792117


Other references

Sitnikova, E.Iu., 1999: The effect of the limitation of afferent inflow in early ontogeny on the evoked activity of projective neurons depends on the degree of the maturity of the sensory inputs. The study is focused on the influence of a partial limitation of the sensory inflow in rat pups on the development of the sensory systems, which mature earlier and later. In accordance with the ontogenetic rule of proximal-distal maturation, the s...

Yagi, N.; Hamada, H.; Sumino, T., 1956: Studies on the milk inhibited lactic acid fermentation.. An inhibition of lactic acid fermentation in raw skim-milk containing L. bulgaricus was observed which was not caused by phage action or by retarding actions due to the presence of putrefactive bacteria or antibiotics in the milk.

Kashfi, K.; Olson, K.R., 2013: Biology and therapeutic potential of hydrogen sulfide and hydrogen sulfide-releasing chimeras. Hydrogen sulfide, H<inf loc="post">2</inf>S, is a colorless gas with a strong odor that until recently was only considered to be a toxic environmental pollutant with little or no physiological significance. However, the past...

Brzeski, M.W., 1992: Enchodelus repis sp. n. and comments on E. laevis Thorne, 1939 and E. microdoroides Baqri & Jairajpuri, 1974 (Nematoda: Dorlaimoidea) from Korea. Enchodelus repis sp. nov. found in an unidentified moss sample from near Kaesong, N. Korea, is characterized by a small (L = 0.81-1.12 mm) and strongly curved body, vulva surrounded by cuticular flaps, cuticle wrinkled near vulva in most females,...

Mahler, D., 1979: Improved method of injecting local anesthetic solutions for breast operations. An improved method of injecting local anesthetic solutions for gynecomastia operations and augmentation mammaplasties is described.

Simonetti, A.; Mastroeni, I.T.rsitani, G., 1971: Clostridium perfringens and induced thermoresistance. Nuovi annali d'igiene e microbiologia: (Pub 1971), 21 (6) 499-511

Crighton, G.; Haeusler, G.; Pati, N.; Connell, T.G., 2011: Pneumocystis jiroveci pneumonia in an infant with severe folate deficiency. Pneumocystis jiroveci pneumonia is rare in immunocompetent children. Severe folate deficiency affects T cell function, potentially increasing susceptibility to opportunistic pathogens. We report the case of an 11-month-old child who developed P. j...

Smolker, Robert E.Reviewer, 1984: Perspectives in ornithology (book review). The Quarterly Review of Biology 59: 5-6

Husson, A.M., 1960: Extra praemolaren in de onderkaak van de mol, Talpa europaea Linnaeus. Lutra(1): 5-8

Pinardi, G.; Leal, E.; Coll, A.S., 1967: Vascular permeability to red blood cells and protein in hemorrhagic shock. Irreversible hemorrhagic shock produces increased output of red blood cells and protein in the thoracic duct lymph of dogs, increased flow of lymph and a slight but consistent reduction in plasma protein content These findings appear in late stage...