geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

The chromatid gap--a useful parameter in genotoxicology?


, : The chromatid gap--a useful parameter in genotoxicology?. Cytogenetics and Cell Genetics 33(1-2): 14-19

Chromatid gaps occur as two morphologically indistinguishable types--the clastogenic (DNA damage) type and the turbagenic (no DNA damage) type--and are induced by many genotoxins in a dose-dependent way. Gaps may serve as a low-dose sentinel parameter in genotoxicology. However, their usefulness is limited until further studies have shown whether the turbagenic substances that cause gaps are all capable of inducing segregational errors. In genetic toxicology testing and monitoring, methanol/acetic acid-fixed and air-dried preparations are stained in Giemsa and are then studied under the light microscope. With this method gaps and breaks cannot be distinguished unambiguously and should therefore be scored in the same class of aberrations.

US$29.90

PMID: 7116936


Other references

Stover, D., 2010: Power to spare. A more robust emergency electrical system. Health Facilities Management 22(1): 21-24

Hiern M.N., 1967: Opal occurrence, Myall Creek station. Common opal in Precambrian bleached zone, Tertiary laterization, no economic value, including an appendix on petrologic descriptions of opal-bearing samples, South Australia.

Imamaki, Kineo, 1932: Studien uber das Endo-theliom des Hundes in Gewebskultur, mit besonderer Berucksichtigung der Natur der Geschwulstzellen. A transplantable and explantable canine endothelioma was reported by the author elsewhere (Mitteil. Path. Inst. Med. Fakult. Niigata 28-36; Jour. Jap. Path. Soc. 21-822.1931; Hokuyetsu-Igakukwai-Zasshi 46-422. 1931). Found in a dog 2 years ago, it...

Boqueras, M.; Diederich, P., 1993: New or interesting lichenicolous fungi: 3. Karsteniomyces llimonae, new species and Sclerococcum serusiauxii, new species (Deuteromycotina). Karsteniomyces llimonae Boqueras and Diederich sp. nov. (Coelomycetes) is distinguished from related species by setose pycnidia, much longer conidiophores and a different host (Parmelina quercina); it is known only from the type locality in Spain...

Snehamoy Chatterji. Rattan Lai. Rahalkar, G.W.; Sethi, G.R.; Saxena, P.N., 1961: Studies on the effects of beta radiations on insects. III. The effect of beta radiations (irradiation of eggs) on the development of Dysdercus koenigii Fabricius. Indian Journal of Entomology, 23: 40-45

Otsuka, Y.; Abe, K.; Saito, T.; Irokawa, N.; Miyazaki, S., 1976: Postoperative course of blood pressure and plasma renin activity in patients with renovascular hypertension. Thirty patients with renovascular hypertension were treated surgically, and they were divided into two groups according to the kinds of operations they received; nephrectomized group (group A) and revascularized group (group B). Postoperative bloo...

Nash, R.G.; Harris, W.G.; Ensor, P.D.; Woolson, E.A., 1973: Comparative extraction of chlorinated hydrocarbon insecticides from soils 20 years after treatment. Three methods (shake, Soxhlet, and column) were compared for efficiency of extraction of certain chlorinated hydrocarbon insecticides from a sandy loam treated 20 years earlier. Column extraction tended to be less efficient than the other two meth...

Radashevsky, Vi, 1993: Recapitulations in the development of spionid polychaetes. Issledovaniya Fauny Morei1993); 43: 62-69 51

Cox, R.S.; Hayslip, N.C., 1957: Notes on current development of gray mold, Botrytis cinerea Fr., of Tomato and its control. In experiments conducted during the 1955-6 season in Florida at the Everglades Experiment Station, Belle Glade, and the Indian River Field Laboratory, Fort Pierce, repeated applications of nabam plus any of a number of metallic salts increased the...

Tang, B.L.; Wong, S.H.; Low, S.H.; Hong, W., 1992: The transmembrane domain of N-glucosaminyltransferase I contains a Golgi retention signal. The enzyme N-acetylglucosaminyltransferase I (NT, EC 2.4.1.101) is a resident type II transmembrane protein of the Golgi apparatus. To delineate the portion of its primary sequence that is responsible for the Golgi retention of this protein, we co...