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The "concrete" histological diagnosis of cerebral tumours of neuroectodermic origin


, : The "concrete" histological diagnosis of cerebral tumours of neuroectodermic origin. Morphologie et Embryologie 29(2): 109-116

The "concrete" histological criteria for establishing the benignity or malignancy of cerebral tumours of neuroectodermic origin (gliomas and medulloblastomas, respectively granulocytomas) may be thus synthetized: 1) the benign tumours have a fibrocellular structure, the neoplastic cells being relatively monomorphous; vascular hyperplasia is absent, as well as necrotic and hemorrhagic foci; 2) the malignant tumours are hyper- and polymorphocellular, the fibrillar component being reduced or absent; vascular hyperplasia as well as the presence of necrotic and/or hemorrhagic foci is a constant characteristic; the tumoral cells often infiltrate the perivascular spaces.

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PMID: 6224078


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