geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Treatment of rheumatoid arthritis with isoprinosine. Personal experience


, : Treatment of rheumatoid arthritis with isoprinosine. Personal experience. Revue du Rhumatisme et des Maladies Osteo-Articulaires 50(10): 653-657

Twenty patients with classical or proved rheumatoid arthritis were treated with Isoprinosine. 13 patients received a dose of 25 mg/kg/day and 7 received a dose of 50 mg/kg/day, continuously for 2 months and then discontinuously, 5 days every fortnight. The series being treated with 25 mg/kg/day (7 patients) have received treatment for 12 months. No side effects have been observed; the only reason for ceasing treatment was its ineffectiveness (after at least 3 months of administration). The dosage of the associated anti-inflammatory drugs did not need to be increased, but neither was it decreased. The authors conclude that Isoprinosine is largely ineffective clinically, on laboratory tests and in terms of immunology, at least with the therapeutic protocols tested here.

US$29.90

PMID: 6196834


Other references

Oh, T-Seok.; Koo, H-Mo.; Yoon, H-Ryeo.; Jeong, N-Su.; Kim, Y-Jin.; Kim, C-Ho., 2015: Antifungal Action of Ginkgo biloba Outer Seedcoat on Rice Sheath blight. From study of antifungal actions on the rice sheath blight by using the extract of Ginkgo biloba outer seedcoats, we found that the extracts of Ginkgo biloba outer seedcoats of all treatment concentrations had inhibited the rice sheath blight. Amo...

Bucala, R.J.; Vlassara, H.; Cerami, A.; Cerami, C.J.; Founds, H.W., 2000: Methods for treatment predicated on the presence of advanced glycosylation endproducts in tobacco and its combustion byproducts. Methods are provided for measuring the accumulation of advanced glycosylation endproducts (AGEs), and for lowering the accumulation of advanced glycosylation endproducts, which are predicated on the discovery that such AGEs and their precedent gly...

Wasilewski, M., 2005: Plant domestication in the New World. The problem of plant domestication in the New World remains still open. The core issue is long or short chronology of this process. Long chronology followers state that plant domestication in the New World begun ~7000/6000 years B.P., whereas acco...

Marinacci, A.A., 1959: Dynamics of neuromuscular diseases. Archives of Neurology 1: 243-257

Brien, Y., 1980: Brittany is in mourning. Recent pollution of beaches by oil has had an effect on the tourist industry in Brittany and Finistere. The tourist image has been polluted. This year only 50% of available holiday accommodation has been booked. Losses in 1978 to the hotel industr...

Egbert B.; Langenbergh A., 1990: Neutrophilic tuberculous panniculitis. Journal of Cutaneous Pathology 17(5): 292

Antoine P.; Fabre D.; Lacombe P.; Menard G., 1994: The geological problems related to the French-Italian railway tunnel under the Alps. Congres International - Association International de Geologie de l'Ingenieur = International Congress - International Association of Engineering Geology 7, Vol

Hinz, J.; Hahn, G.; Neumann, P.; Sydow, M.; Mohrenweiser, P.; Hellige, G.; Burchardi, H., 2003: End-expiratory lung impedance change enables bedside monitoring of end-expiratory lung volume change. The aim of the study was to investigate the effect of lung volume changes on end-expiratory lung impedance change (ELIC) in mechanically ventilated patients, since we hypothesized that ELIC may be a suitable parameter to monitor lung volume change...

van den Broek, P., 1970: Experiments with ossicular grafts. Acta Oto-Rhino-Laryngologica Belgica 24(1): 79-82

Wake, Marvalee H.Reviewer, 1986: Reproduction in mammals (book review): V4. The Quarterly Review of Biology 61: 7