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Typical and atypical mast cells of the rat gastrointestinal system: distribution and correlation with tissue histamine


, : Typical and atypical mast cells of the rat gastrointestinal system: distribution and correlation with tissue histamine. Agents and Actions 14(1): 1-7

Mast cells and histamine are present throughout the rat gastrointestinal system. Typical mast cells, differentiated from atypical mast cells by morphology, staining characteristics, and response to Compound 48/80, were the only mast cell type identified by histology in the cheek, tongue, esophagus, and nonglandular stomach. Atypical mast cells were found in large numbers in the glandular stomach, small and large intestine, and cecum, where they outnumbered typical mast cells by up to 20:1. Gastrointestinal histamine levels varied from 2.6 to 19.3 ng/mg in all tissues surveyed except for the glandular stomach, which contained 26 ng/mg. The amount of histamine per typical mast cell was estimated to be approximately 1.29 picograms; atypical mast cells contained less than 0.15 picograms per cell. Parenteral administration of Compound 48/80 resulted in the degranulation of typical mast cells, but not atypical mast cells, as determined by a fall both in typical mast cell number and a decrease in tissue histamine in areas rich in typical mast cells. These results indicate that striking regional differences in mast cell distribution and tissue histamine levels exist in the rat gastrointestinal system.

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PMID: 6702506


Other references

Blanc, Fédéric.; Sperrin, L.; Jefferson, D.A.; Pawsey, S.; Rosay, M.; Grey, C.P., 2013: Dynamic nuclear polarization enhanced natural abundance 17O spectroscopy. We show that natural abundance oxygen-17 NMR of solids could be obtained in minutes at a moderate magnetic field strength by using dynamic nuclear polarization (DNP). Electron spin polarization could be transferred either directly to (17)O spins o...

Khaleel Basha, S.; Govindaraju, K.; Manikandan, R.; Ahn, J.Seog.; Bae, E.Young.; Singaravelu, G., 2010: Phytochemical mediated gold nanoparticles and their PTP 1B inhibitory activity. Current discovery demonstrates the rapid formation of gold nanoparticles with guavanoic acid a phytochemical of Psidium guajava (Pg). The pharmacological capabilities of the phytochemicals present in the leaves of Pg and their ability to generate...

Xu, Y., 2013: Quaternion-based discriminant analysis method for color face recognition. Pattern recognition techniques have been used to automatically recognize the objects, personal identities, predict the function of protein, the category of the cancer, identify lesion, perform product inspection, and so on. In this paper we propos...

Morales, M.A.; Ahumada, F.; Castillo, E.; Burgos, R.; Christen, P.; Bustos, V.; Muñoz, O., 2013: Inhibition of cholinergic contractions of rat ileum by tkopane-type alkaloids present in Schizanthus hookeri. The relative lack of specificity of atropine as a competitive antagonist of muscarinic receptors is a frequent cause of undesirable parasympathetic side effects. Consequently, new tropane alkaloids with potentially greater selectivity are usually...

Corazza, M.; Lauriola, M.Michela.; Mantovani, L.; Virgili, A., 2006: Allergic contact dermatitis due to orthopedic shoes and a prosthesis for an amputated foot. Contact Dermatitis 55(2): 115-117

Buendia-Rodriguez,J.A.; Lopez-Gutierrez,J.J.; Garcia-Vega,O.A.; Diaz-Rojas,J.; Sanchez-Villamil,J.P., 2008: Drug prescription patterns in patients attended at a middle- and high-complexity level institution. In this cross-sectional study, medication prescriptions were evaluated in 331 second- and third-level complexity hospitals located in 27 Colombian departments during 2006. In total, 38 863 prescriptions for 3663 patients' medications were ana...

Stogov, IA.; Movchan, EA.; Polyakova, NV.; Sukhoparova, EYu., 1996: Physical-chemical and biological characteristics of rockpools of the Keret Archipelago (the Kandalaksha Bay, the White Sea) in 1990-1994. Vestnik Sankt-Peterburgskogo Universiteta Seriya 3 Biologiya. mai; 2: 17-23, 115 No 10

Dickins J.M., 2000: The northern margin of Gondwanaland; Uppermost Carboniferous to Lowermost Jurassic and its correlation. Developments in Palaeontology and Stratigraphy: ages 257-270. 2000.

Keret, D.; Kam, I.; Ben-Arieh, Y.; Hashmonai, M., 1990: Scrotal cavernous haemangioma with a family history of cutaneous angiomata. Journal of the Royal Society of Medicine 83(6): 402-403

Blanchet, K.D., 1996: Current management practices in the treatment of Pneumocystis carinii pneumonia (PCP). Aids Patient Care and Stds 10(2): 116-121