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Uterine leiomyomas, serum cholesterol, and oral contraceptives. A preliminary study of epidemiologic differences in Los Angeles, California and Albany, New York

, : Uterine leiomyomas, serum cholesterol, and oral contraceptives. A preliminary study of epidemiologic differences in Los Angeles, California and Albany, New York. Diagnostic Gynecology and Obstetrics 4(1): 21-24

In order to determine the feasibility of a large-scale study to investigate the relationship of serum cholesterol levels to the presence or absence of uterine leiomyomas, the medical records of 67 women aged from 30 to 39 who underwent hysterectomies at UCLA Hospital, Los Angeles, and Albany Medical Center, Albany, New York were reviewed. The women at UCLA were more likely to have a history of oral contraceptive use than were the women in Albany; they also had higher serum cholesterol values. In both hospitals, increasing age was associated with the presence of leiomyomas, and oral contraceptive use was associated with absence of pathology in the resected uterus. In Albany, but not in Los Angeles, oral contraceptive uterus. In Albany, but not in Los Angeles, oral contraceptive use was associated with elevated serum cholesterol, As expected, uterine weight and presence of leiomyomas were strongly associated. It was concluded that serum cholesterol levels were apparently unrelated to presence of uterine leiomyomas and to uterine weight in this group of women. Recommendations are made for the design of a case-control study to further investigate both the cholesterol-leiomyoma relationship and the other results reported here.


PMID: 7075443

Other references

Brock, H.W.; Roberts, D.B., 1982: The LSP1-alpha gene is not dosage compensated in the Drosophila melanogaster species subgroup. Biochemical Genetics 20(3-4): 287-296

Endoh M.; Nakase Y., 1985: Purification and characterization of bordetella heat labile toxin. Japanese Journal of Medical Science & Biology 38(2): 83

Park, Y.M.; Matsumoto, K.; Shinkoda, H.; Nagashima, H.; Kang, M.J.; Seo, Y.J., 2001: Age and gender difference in habitual sleep-wake rhythm. We analysed the effects of age and gender on the habitual sleep-wake rhythm in 2252 randomly selected subjects living in Shimonoseki, Japan. Subjects were divided into 21 age groups with a matching number of males and females for each. During the...

Polotskaia, A.; Wang, M.; Patschan, S.; Addabbo, F.; Chen, J.; Goligorsky, M.S., 2007: Regulation of arginine methylation in endothelial cells: role in premature senescence and apoptosis. With the recent characterization of enzymes responsible for protein arginine methylation and demonstration that catabolic products of arginine methylation, such as asymmetric dimethylarginine (ADMA), are among the most powerful mechanisms of ather...

Argles Tom; Foster Gavin; Whittington Alan; Harris Nigel; George Mark, 2003: Isotope studies reveal a complete Himalayan section in the Nanga Parbat syntaxis. Many models of orogenesis invoke simple anatomies for mountain belts, comprising a small number of major tectonic provinces separated by major faults. In the Himalayan arc, three main tectonic provinces (the Lesser Himalayan, High Himalayan and Te...

Bhattacharyya Ajit; Chanda S.K., 1971: Petrography and origin of the Krol Sandstone around Solon, Himachal Pradesh. Journal of the Geological Society of India 12(4): 368-372

Liu, H-Wen.; Chan, Y-Ching.; Wei, C-Chun.; Chen, Y-An.; Wang, M-Fu.; Chang, S-Joan., 2017: An alternative model for studying age-associated metabolic complications: Senescence-accelerated mouse prone 8. Rodent animal models take at least 18months to develop aging phenotypes for researchers to investigate the mechanism of age-related metabolic complications. Senescence-accelerated mouse prone 8 (SAMP8) shortens the process of aging and may facilit...

Lilley, R.; Goyal, A.M.rengo, T.B.own, A., 1987: The responses of Dunaliella to salt stress: a comparison of effects on photosynthesis, and on the intracellular levels of the osmoregulatory solute glycerol, the adenine nucleotides and the pyridine nucleotides. Progress in photosynthesis research: proceedings of the VIIth International Congress on Photosynthesis Providence Rhode Island USA ust 10-15-1986 edited by J Biggins: 196

Wong, C-Ho.; Tan, B-Keem., 2008: Necrotizing fasciitis of the breast. Plastic and Reconstructive Surgery 122(5): 151e-152e

O'dowd B.F.; Hnatowich M.; Caron M.G.; Lefkowitz R.J.; Bouvier M., 1989: Palmitoylation of the human beta 2 adrenergic receptor mutation of cysteine in the carboxyl tail leads to an uncoupled nonpalmitoylated form of the receptor. We report that a cysteine residue in the human .beta.2-adrenergic receptor (.beta.2AR) is covalently modified by thioesterification with palmitic acid. By site-directed mutagenesis of the receptor, we have identified Cys341 in the carboxy tail of...