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Anti-Toxoplasma gondii immunoglobulins A and G in human saliva and serum

, : Anti-Toxoplasma gondii immunoglobulins A and G in human saliva and serum. Journal of Oral Pathology & Medicine 26(4): 187-191

Paired human saliva and serum samples from 60 individuals were tested for specific IgA and IgG antibodies to Toxoplasma gondii. The study in both fluids was carried out by indirect immunoenzymatic assay (ELISA). Saline antigenic extract of T. gondii was used to coat plastic surfaces upon which the samples were then incubated; monospecific conjugates of anti-IgA and anti-IgG-peroxidase were then incubated with the samples after a washing procedure to separate the unbound antibodies. The enzymatic activity was measured and the results expressed in terms of ELISA index. Toxoplasma-specific IgG antibodies were detected in 43 of the serum samples (71.7%) and in 12 of the saliva samples (20.0%) whereas Toxoplasma-specific IgA antibodies were detected in 18 of the serum samples (30.0%) and in 12 of the saliva samples (20.0%). No association was observed when the Toxoplasma-specific IgG reactive and non-reactive serum samples were compared with the reactive and non-reactive saliva samples for this class of immunoglobulin. On the other hand, a significant association was observed when the Toxoplasma-specific IgA reactive and non-reactive serum samples were compared with the reactive and non-reactive saliva for this type of antibody. In conclusion, our results show that the detection of salivary IgA reflects the serum level of this isotype but salivary IgG does not. Moreover, the isolated detection of salivary IgG may not contribute to epidemiological studies of chronic toxoplasmic infections.


PMID: 9176794

Other references

Lorhan, P.H., 1967: Tracheoesophageal cleft. Anesthesiology: 633-634

Ignatius M.J.; Reichardt L.F., 1988: Identification and characterization of a neuronal laminin receptor an integrin heterodimer that binds laminin in a divalent cation dependent manner. Journal of Cell Biology 107(6 PART 3): 799A

Yoshida H.; Morita I.; Tamai G.; Masujima T.; Tsuru T.; Takai N.; Imai H., 1984: Some characteristics of a protein coated octadecylsilyl column and its use for the determination of drugs by direct injection analysis of plasma samples. Chromatographia 19: 466-472

Mora, N.; Rachidi, F.; Rubinstein, M., 2012: Application of the time reversal of electromagnetic fields to locate lightning discharges. In this paper, we propose a new method for locating lightning discharges. The proposed method is based on the time reversal technique introduced for acoustics in the early 199s. By analogy to the derivations in acoustics, equations for the focusin...

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Suzuki, N.; Cheung, T.T.; Cai, X.D.; Odaka, A.; Otvos, L.; Eckman, C.; Golde, T.E.; Younkin, S.G., 1994: An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants. Normal processing of the amyloid beta protein precursor (beta APP) results in secretion of a soluble 4-kilodalton protein essentially identical to the amyloid beta protein (A beta) that forms insoluble fibrillar deposits in Alzheimer's diseas...

Kim E.; N.K.J., 1990: Acute toxic effect of sodium dichromate on metabolism. The effect of sodium dichromate on cellular metabolism was investigated. Intraperitoneal injection of sodium dichromate into the rat (20 or 40 mg/kg) caused significant increases in serum lactate, pyruvate, and creatinine concentrations within 15...

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Salgado, E.; Selye, H., 1954: The role of the thyroid in the production of cardiovascular and renal changes by methylandrostenediol. Journal of Endocrinology 11(4): 331-337