geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

CuraGen Corporation


, : CuraGen Corporation. Pharmacogenomics 3(4): 551-554

CuraGen Scientists have developed a deep preclinical pipeline of potential protein, antibody and small molecule therapeutics by integrating expertise in molecular biology with a proprietary suite of functional genomic technologies. One important application of functional genomics is in the area of pharmacogenomics, which has been a critical component in CuraGen's drug discovery and development efforts. By identifying safety and efficacy issues early in the discovery process and by gaining a better understanding of a drug's mechanism of action, CuraGen scientists are able to make more informed decisions about which drugs are the most appropriate to advance through the preclinical and clinical development stages.

US$19.90

PMID: 12164777

DOI: 10.1517/14622416.3.4.551


Other references

Jezela-Stanek, A.; Kucharczyk, M.; Falana, K.; Jurkiewicz, D.; Mlynek, M.; Wicher, D.; Rydzanicz, M.; Kugaudo, M.; Cieslikowska, A.; Ciara, E.; Ploski, R.; Krajewska-Walasek, M., 2016: Malan syndrome (Sotos syndrome 2) in two patients with 19p13.2 deletion encompassing NFIX gene and novel NFIX sequence variant. Sotos syndrome 2 (MIM #614753), known also as Malan syndrome, is caused by heterozygous mutations/deletions of the NFIX gene located on chromosome 19p13.2. It manifests in developmental delay, intellectual impairment, macrocephaly, central nervous...

Van Enoo, R.E., 1991: Soft-tissue bunionectomy with first metatarsal ostectomy using minimal incision technique. Correcting a mild to moderate bunion deformity through a partial ostectomy of the first metatarsal head and soft-tissue release around the first metatarsophalangeal joint can be done safely and effectively through a minimal incision approach. The...

Kurazumi, H.; Kubo, M.; Ohshima, M.; Yamamoto, Y.; Takemoto, Y.; Suzuki, R.; Ikenaga, S.; Mikamo, A.; Udo, K.; Hamano, K.; Li, T-Sheng., 2012: The effects of mechanical stress on the growth, differentiation, and paracrine factor production of cardiac stem cells. Stem cell therapies have been clinically employed to repair the injured heart, and cardiac stem cells are thought to be one of the most potent stem cell candidates. The beating heart is characterized by dynamic mechanical stresses, which may have...

Verescagin, G.; Ju., 1912: Die Cladoceren des Sees von Skutari und einiger benachbarter Gewasser. Varsava Rab zool lab Univ, 162-193

Cao, Y.; Chen, F.; Li, Y.; Wei, S.; Wang, G., 2015: Paenibacillus ferrarius sp. nov., isolated from iron mineral soil. A Gram-reaction-positive, endospore-forming, aerobic bacterium, designated strain CY1(T), was isolated from iron mineral soil of Hunan Province, China. The isolate was rod-shaped and motile by means of peritrichous flagella. The major cellular fat...

Krivovichev Sergey V.; Filatov Stanislav K.; Burns Peter C., 2002: The cuprite-like framework of OCu (sub 4) tetrahedra in the crystal structure of synthetic melanothallite, Cu (sub 2) OCl (sub 2) , and its negative thermal expansion. The Canadian Mineralogist 40, Part 4: 1185-1190

Joda, A.E.; Fanimokun, T.O., 2008: Acceptance of ACTs by patients in private healthcare facilities in Surulere, Lagos State. Chloroquine has remained the first line in the management of malaria for over five decades. The avalanche of published research works and books on Chloroquine attests to its success and usefulness. Although, Chloroquine and Sulfadoxine / Pyrimetha...

Russell, J.; Katzhendler, J.; Kowalski, K.; Schneider, A.B.; Sherwood, L.M., 1981: The single tryptophan residue of human placental lactogen. Effects of modification and cleavage on biologic activity and protein conformation. In order to define further the chemical features of the human placental lactogen (hPL) molecule responsible for its lactogenic activity, two derivatives of the hormone were prepared by treatment with BNPS-skatole (2-nitrophenylsulfenyl)-3-methyl-3...

Fasanmade, O.A.; Dagogo-Jack, S., 2016: Diabetes Care in Nigeria. Diabetes is a noncommunicable disease that has attained great significance in the sub-Saharan region, with Nigeria being the most affected. Many persons with the condition suffer a reduced life expectancy and quality of life. Diabetes places an ex...

Perry, M.D.; Manoli, A., 2012: Reconstruction of the foot after leg or foot compartment syndrome. Critical Care Nursing Clinics of North America 24(2): 311-322