geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Curative resection for colorectal cancer in the elderly. Prognostic factors and five-year follow-up


, : Curative resection for colorectal cancer in the elderly. Prognostic factors and five-year follow-up. Annali Italiani di Chirurgia 71(4): 491-6; Discussion 496-7

The purpose of this perspective study was to evaluate which prognostic factors predict long-term survival and disease-free survival (DFS) of elderly patients (> or = 65 years) who underwent surgery for colorectal carcinoma. Between January 1992 and December 1998, 196 colorectal cancer patients > or = 65 years (114 M; 82 F; mean age: 75 years; range: 65-92) underwent surgery. One hundred forty-five (74%) of them underwent curative surgery and emergency surgery was more common in patients > or = 75 years of age than among those younger than 75 years (39% vs 23%; p = 0.01). The overall peroperative mortality rate was 3% (n = 6). The median length of hospital stay was 18 days (range: 3-86 days). By univariate analysis, intraoperative bleeding (> or = 500 cc; p = 0.002), length of surgery (> or = 240 min.; p = 0.004), and rectal cancer (p = 0.0001) were associated with complications. By multivariate analysis, only rectal cancer (p = 0.002) was associated with complications. The overall 1, 3-, and 5-year survival rate and DFS rate were 97%, 82%, 74%, and 86%, 64% and 60% respectively. Using multivariate analysis only tumour stage (p < 0.0001) and peroperative blood transfusions (> or = 500 cc; p = 0.006) were associated with outcome. Treatment decisions in elderly patients with colorectal carcinoma should not be influenced by the chronologic age of the patient.

US$29.90

PMID: 11109674


Other references

Rachid, R.A.; Bonilla, F.A.; Grant, B.L.; Twarog, F.J.; Leslie, D.S., 2000: Evaluation of anaphylaxis to multiple corticosteroids in a patient with Juvenile Rheumatoid Arthritis. Journal of Allergy & Clinical Immunology 105(1 part 2): S348, Jan

Washington, W.; Rodney, H., 1986: How do students learn about natural-resource careers?. Journal of forestry 84(10): 22-24

Christoffel D.A., 1975: Motion along the New Zealand Alpine Fault and a model for the formation of the Southern Alps. Bulletin - Australian Society of Exploration Geophysicists 6(2-3, First Southwest Pacific workshop-symposium): 55

Muma, M.H., 1964: Cheyletidae (Acarina : Trombidiformes) associated with citrus in Florida. Florida Entomologist, 47: 239-253

Koeck, G.P.; Jacobson, L.E.; Hillsinger, W.R., 1962: Cobalt-60 teletherapy of cancer of the cervix by a rotation technic. Preliminary report. Radiology 79: 190-202

Thiel, C.; Wills, D.; Foing, B.; Wadham, J.; Cullen, D.; van Sluis, C., 2009: PCR-based analysis of microbial communities in extreme environment; results from EuroGeoMars MDRS campaign. Geophysical Research Abstracts 11

Anonymous, 1984: Proceedings of the Workshop on Evaluation of Therapy. September 1983. Bethesda, MD. Statistics in Medicine 3(4): 305-478

Newcomb, P.A.; Lantz, P.M., 1993: Recent trends in breast cancer incidence, mortality and mammography. The recent trends in mammography, and in breast cancer incidence and mortality, demonstrate the impact of an effective cancer control effort. The number of women over age 40 years who have ever had mammography has increased over 200% since 1980. C...

Chin, S.Shien.; Romano, R-Anne.; Nagarajan, P.; Sinha, S.; Garrett-Sinha, L.Ann., 2013: Aberrant epidermal differentiation and disrupted ΔNp63/Notch regulatory axis in Ets1 transgenic mice. The transcription factor Ets1 is expressed at low levels in epidermal keratinocytes under physiological conditions, but is over-expressed in cutaneous squamous cell carcinoma (SCC). We previously showed that over-expression of Ets1 in differentiat...

Rubinstein, C.Jorge.; Faucault, P.Michel., 2015: Medicine: 30 years after the death of the great humanist. International Journal of Emergency Mental Health 16(2): 272-273