geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Current and future strategies for combined-modality therapy in pancreatic cancer


, : Current and future strategies for combined-modality therapy in pancreatic cancer. Current Oncology Reports 4(3): 202-212

Treatment of pancreatic cancer remains a challenging task that often requires a multidisciplinary approach to confer optimal response and, ideally, maximize survival. A combination of locoregional approaches such as surgery and radiotherapy, along with systemic therapies for eradication of micrometastases, should be considered both for patients who are operative candidates and for those with locally advanced, unresectable disease. How best to combine these modalities in terms of schedule, timing, and choice of agents is a question that continues to be actively investigated. Some of these data are equivocal or conflicting; thus standards of care for combined-modality treatment have not been uniformly accepted to date. This article provides an overview of combined-modality therapy, focusing on the major studies that have guided our current approach to the treatment of pancreatic cancer and examining new strategies that are likely to improve outcomes and survival for patients in the future.

US$29.90

PMID: 11937010


Other references

Harris, G.J.; Dixon, T.A.; Haughton, V.M., 1983: Expansion of the lacrimal gland fossa by a lymphoid tumor. American Journal of Ophthalmology 96(4): 546-547

Frund, H-C., 1989: Untersuchungen zur Biologie stadtischer Boden. 5. Epigaische Raubarthropoden. Verhandlungen der Gesellschaft fuer Oekologie. 1988 ; 18: 201-209

Robb J.; Hitchmough R.A., 1979: Review of the genus naultinus reptilia gekkonidae. Records of the Auckland Institute & Museum 16: 189-200

Anonymous, 2011: Extinction of Larger Benthic Foraminifera at the Eocene / Oligocene boundary. A number of long-ranging and widespread larger benthic foraminiferal taxa are known to have become extinct during the Eocene Oligocene transition. However, detailed records through the transition are rare, and few complete sections are known. Here...

Shi, L.; Chen, J.; Zhong, Q.; Li, M.; Geng, P.; He, J.; Han, Z.; Sheng, M.; Tang, H., 2014: Inactivated Sendai virus strain Tianjin, a novel genotype of Sendai virus, inhibits growth of murine colon carcinoma through inducing immune responses and apoptosis. Journal of Translational Medicine 11: 205-205

Noma, T.; Yoon, Y.S.ik; Nakazawa, A., 1999: Overexpression of NeuroD in PC12 cells alters morphology and enhances expression of the adenylate kinase isozyme 1 gene. NeuroD, a basic helix-loop-helix transcription factor, plays an important role in neuronal differentiation. A rat NeuroD cDNA was obtained by the aid of reverse transcription-polymerase chain reaction (RT-PCR) and ligated to an expression vector h...

Fuller, A.T.; Hawking, F.; Partridge, M.W., 1942: The effect of various media on the rate of absorption of sulphanilamide. In vitro, the absorption of sulfanilamide after local application was much delayed by the incorporation of the sulfanilamide in an oily base or in a water-in-oil emulsion; it was not much influenced by incorporation in a glycerin-gelatin base, or...

Fleitout Luce; Froidevaux Claude, 1982: State of stress and mass heterogeneites in the lithosphere. Terra Cognita 2(2): 156-157

Salo, M.L., 1978: Ensiling, preservation losses and effluent binding of sugar beet tops. Data are given on contents of mineral elements and of organic constituents (including CP, sugars, water-sol. organic acids, CF, ash, lignin, cellulose and hemicellulose) in sugar beet tops harvested by mower-chopper and before and after ensiling....

L.Y.n; Ren Yi; Jia Hui, 2003: The taxonomic studies on the bamboo as the main food of giant panda from Mt. Qinling. Five wild bamboo species belonging to 4 genera are found in the Changqing National Nature Reserve. Most of these species are the main food of giant pandas. Bashania fargesii is mainly distributed at <1800- to 2000-m elevations. Fargesia qinling...