+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Diagnosis and treatment of tuberculosis in Spain: results of the Multicenter Project for Tuberculosis Research

, : Diagnosis and treatment of tuberculosis in Spain: results of the Multicenter Project for Tuberculosis Research. Medicina Clinica 116(5): 167-173

To analyze clinical practice regarding tuberculosis in Spain. After active search in 14 registries, cases of tuberculosis were identified in 13 autonomous regions, representing almost 67% of the total Spanish population. The study period was May 1996-April 1997. 10,053 cases were identified. Almost 80% were diagnosed at the hospital and most of the patients (91.7%) were symptomatic. Median patient delay was 21 days and median delay between symptoms and treatment was 41 days. Smear and culture was performed in 82% of pulmonary cases while at least a culture was performed in 75.5% of extrapulmonary cases. 72.5% of pulmonary cases and 39.7% of extrapulmonary cases were culture positive. More than 76% of the subjects were treated with 3 drugs, generally rifampin, isoniazid and pirazinamide in agreement with Spanish guidelines; however, the information on duration of treatment was insuficient. Combined tablets were usually prescribed (86.8% of patients) and use of DOT was scarce (5.4% of cases). The information on contact investigation was poor. Diagnostic and treatment practices regarding tuberculosis have clearly improved in Spain, but patient management has still to improve.


PMID: 11222172

Other references

Donate, F.; Kelly, C.R.; Ruf, W.; Edgington, T.S., 2000: Dimerization of tissue factor supports solution-phase autoactivation of factor VII without influencing proteolytic activation of factor X. Tissue factor (TF) is a transmembrane receptor that initiates the thrombogenic cascade by assembly with the serine protease factor VII or VIIa (VII/VIIa) resulting in formation of the bimolecular active complex TFcntdotVIIa. Chemical cross-linking...

Lin, J.; Baghikar, S.; Mauntel-Medici, C.; Heinert, S.; Patel, D., 2017: Patient and System Factors Related to Missed Opportunities for Screening in an Electronic Medical Record-driven, Opt-out HIV Screening Program in the Emergency Department. Emergency departments (EDs) have implemented HIV screening using a variety of strategies. This study investigates how specific patient and health system factors in the ED impact who is and is not screened in a combined targeted and nontargeted, el...

Morycowa Elzbieta; Marcopoulou Diacantoni Anastasia, 2002: Albian corals from the Subpelagonian Zone of central Greece (Agrostylia, Parnassos region). Annales Societatis Geologorum Poloniae: , Pages 1-65. 2002.

Bartlett, S.T.; Schweitzer, E.J.; Roberts, J.E.; Jaekels, J.L.; Sandager, G.L.; Johnson, L.B.; Killewich, L.A., 1995: Early experience with a new ePTFE vascular prosthesis for hemodialysis. An expanded polytetrafluoroethylene (ePTFE) graft for hemodialysis designed for immediate cannulation was tested. The graft contains a cannulation segment consisting of a stretch ePTFE base tube surrounded by flat and round ePTFE fibers that are s...

Dulger,B.; Hacioglu,N., 2008: Evaluation of antimicrobial activity of two endemic Scrophulariaceae members. Asian Journal Of Chemistry: 8, 6385-6390

D.P.tter P.; Shields C.L.; Shields J.A.; Flanders A.E.; Rao V.M., 1992: Role of magnetic resonance imaging in the evaluation of the hydroxyapatite orbital implant. The role of magnetic resonance imaging (MRI) in the assessment of fibrovascular ingrowth in the integrated hydroxyapatite orbital implant is evaluated. Fifteen patients who underwent enucleation and placement of a hydroxyapatite orbital implant we...

Kaden, U.; Roemer, W.; Wondraczek, R., 1988: Isolation and characterization of streptavidin. Die Pharmazie 43(7): 512-513

Bek, B.; Boeckh, M.; Lepenies, J.; Bieniek, B.; Arasteh, K.; Heise, W.; Deppermann, K.M.; Bornhöft, G.; Stöffler-Meilicke, M.; Schuller, I.; Höffken, G., 1996: High-level sensitivity of quantitative pp65 cytomegalovirus (CMV) antigenemia assay for diagnosis of CMV disease in AIDS patients and follow-up. Cytomegalovirus (CMV) antigenemia was evaluated in 174 patients positive for human immunodeficiency virus. Antigenemia could be detected in 96.7% of patients with CMV disease, 76.9% of patients suffering from a relapse of the disease, and 11.4% of...

Hafez, A.H.; Megalla, S.E., 1982: The potential value of silage in detoxifying aflatoxin B1. Serial concentrations of aflatoxin B1 ranging from 200 to 1500 p.p.b. in 2% lactic acid solution (which is the aimed concentration of lactic acid in fresh silage) were assayed for detoxification. Thin-layer chromatography analysis, revealed a comp...

Watanabe, K.; Dohi, K.; Sugimoto, T.; Yamada, T.; Sato, Y.; Ichikawa, K.; Sugiura, E.; Kumagai, N.; Nakamori, S.; Nakajima, H.; Hoshino, K.; Machida, H.; Okamoto, S.; Onishi, K.; Nakamura, M.; Nobori, T.; Ito, M., 2013: Short-term effects of low-dose tolvaptan on hemodynamic parameters in patients with chronic heart failure. We evaluated the short-term effects of low-dose tolvaptan treatment on hemodynamic parameters in patients with chronic heart failure (HF). We studied 22 patients (69<hsp sp="0.25"/> <hsp sp="0.25"/>10 years) with ch...