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Expression of rat type 2C alpha protein phosphatase in Saccharomyces cerevisiae cells


, : Expression of rat type 2C alpha protein phosphatase in Saccharomyces cerevisiae cells. Gan to Kagaku Ryoho. Cancer & ChemoTherapy 21(3): 325-329

In the course of a study to elucidate the physiological functions of type 2C protein phosphatase(PP2C), we investigated the effects of overexpression of the enzyme protein on the physiology of eukaryotes. In this study, we demonstrated that the overexpression of PP2C alpha caused a decreased growth rate and an increased UV-sensitivity of the yeast cells. We also showed that the expressed PP2C was phosphorylated by casein kinase II in the cells.

US$29.90

PMID: 8109987


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