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How will pharmacogenetics impact the future of research and development?


, : How will pharmacogenetics impact the future of research and development?. Drug Discovery Today 6(2): 59-60


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PMID: 11166244


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Lila, T.; Natsoulis, G.; Phillips, J.; Wilson, L.; Cope, M.J.; Renau, T.E.; Watkins, W.J.; Buysse, J., 2001: A novel chemical series demonstrating fungal-specific inhibition of tubulin polymerization. Compounds in the MC 305904 series selectively inhibit the growth of a Saccharomyces cerevisiae alpha tubulin mutant strain, and have been shown to selectively inhibit mitotic spindle function in fungal versus cultured human cells. In this work, we...

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