geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Internal carotid artery dissection: an animal model?


, : Internal carotid artery dissection: an animal model?. Journal of Investigative Surgery 11(1): 63-68

This paper describes an internal carotid artery (ICA) dissection model in a rabbit. An animal model for ICA dissection has not been described. New Zealand White rabbits were anaesthetized and surgical microdissection performed to expose the right internal carotid artery. A small arteriotomy was performed and a subadventitial plane of dissection created using blunt dissection and injected heparinized saline. The adventitia was sutured and the animals were recovered after closure of the wound. The procedure was repeated on the left ICA after 7 days with removal of the left ICA for control samples and removal of the right ICA to obtain sample specimens. The brain was also removed. A total of 11 control specimens and 9 sample specimens were obtained. The mean length of these specimens (n = 20) was 5.5 mm (range 5-6 mm). The mean length of dissection of the control specimens (n = 11) was 2.2 mm (range 2-3 mm). The mean length of dissection on sample specimens (n = 9) was 2 mm (range 1-3 mm). There was no extension of the arterial dissection. There was no intraluminal thrombosis or cerebral infarction. This model was able to induce arterial wall dissection in a rabbit. There was no extension of the induced dissection over 7 days. No local arterial or cerebral ischemic complications developed from the dissection.

US$29.90

PMID: 9659638


Other references

Su, Q.; Xie, D.; Zhang, J.; Du, G.; Xu, B., 2013: In situ transmission electron microscopy observation of the conversion mechanism of Fe2O3/graphene anode during lithiation-delithiation processes. Transition metal oxides have attracted tremendous attention as anode materials for lithium ion batteries (LIBs) recently. However, their electrochemical processes and fundamental mechanisms remain unclear. Here we report the direct observation of...

Tissut, M.R.vanel, P., 1980: Distribution of flavonols in the leaf epidermis of some vascular plants. Phytochemistry 9(10): 2077-2081

Krist, G., 1965: Sanding of peat grassland. Results from 5 years of investigations on a sanding trial plot in Drenthe (1959-1963). Poor quality marshy grassland on peat soil, containing over 30% Deschampsia cespitosa, was ploughed and covered with a layer of sand 6, 12 or 18 cm deep before sowing a perennial ryegrass/meadow fescue/timothy/ rough-stalked meadowgrass/white clov...

Rowan, J.O.; Robertson, J.S., 1970: Evaluation of surgical ventricular shunts using sodium pertechnetate (Na99Tcm04). British Journal of Radiology 43(515): 831-831

Pedersen, M.; Nielsen, P.B.; Permin, H.; Norn, S.; Mojon, M.; Skov, P.S.; Faber, V., 1989: Type I reactions directed against Pneumocystis carinii in AIDS patients. Type I allergy directed against Pneumocystis carinii (PC) has been investigated in 14 patients with AIDS. The Pneumocystis carinii pneumonia often shows a rapid and severe course, and type I allergy against the parasite might be a pathogenic co-fa...

Kurdjukov, M.G., 1967: The relationship of live weight to egg production and egg weight in various breeds of fowl. Egg production and egg weight increased as body weight increased up to 2.2, 2.9 and 2.6 kg. in Russian Whites, Ukrainian Clays and Australorps resp., and decreased thereafter.

Zhang, S-Jin.; Sandström, M.E.; Lanner, J.T.; Thorell, A.; Westerblad, Håkan.; Katz, A., 2007: Activation of aconitase in mouse fast-twitch skeletal muscle during contraction-mediated oxidative stress. Aconitase is a mitochondrial enzyme that converts citrate to isocitrate in the tricarboxylic acid cycle and is inactivated by reactive oxygen species (ROS). We investigated the effect of exercise/contraction, which is associated with elevated ROS...

Meneghetti, P.; Scapellato, M.L.; Marcuzzo, G.; Priante, E.; Bartolucci, G.B., 1992: Pollution by nitrous dioxide during diagnostic laparoscopy interventions. Here we have outlined the data relative to an environmental survey carried out in a laparoscopy clinic at the hospital of Padua, to determine the environmental concentration of nitrous dioxide (N2O) used for intra-abdominal inflation during diagno...

McClure, E.M.; Dudley, D.J.; Reddy, U.M.; Goldenberg, R.L., 2010: Infectious causes of stillbirth: a clinical perspective. Untreated infection may cause stillbirth by several mechanisms, including direct fetal infection, placental damage, and severe maternal illness. Many bacteria, viruses, and protozoa have been associated with stillbirth. In developed countries, up...

Anonymous, 1971: Resolutions adopted at the ninety-ninth annual meeting in minneapolis, Minnesota. American Journal of Public Health 61(12): 2524-2544