geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Localization of sex hormone-binding globulin mRNA expression in human uterine endometrium


, : Localization of sex hormone-binding globulin mRNA expression in human uterine endometrium. Gynecological Endocrinology 11(1): 1-4

To identify the dominant cell of sex hormone-binding globulin (SHBG) synthesis in human uterine endometrium, we investigated the expression of endometrial SHBG mRNA using Northern blot and in situ hybridization analyses. Expression of a single dominant SHBG mRNA was detected in uterine endometrium using Northern blot analysis. Additionally, SHBG mRNA expression was demonstrated by in situ hybridization in the glandular epithelial cells of the endometrium, but not in the stromal cells. Therefore, in the endometrial glandular epithelial cells, SHBG might be involved in the intracellular steroidal action, but not in the endometrial stromal cells. The SHBG-mediated effects on the endometrium appear to be heterogeneous.

US$29.90

PMID: 9086331


Other references

Kawase, M.; Hosono, A., 1995: Binding Stability of Lactic Acid Bacterial Cells with Mutagenic Tryptophan Pyrolysates. The aim of the present study was to investigate the stability of binding mutagenic tryptophan pyrolysates such as Trp-P1 and Trp-P2 to Lactobacillus casei subsp. casei R-52 cells. Stability was estimated by quantifying the amount of Trp-P1 or Trp-...

Prada-Delgado, O.; Barge-Caballero, E.; Peteiro, Jús.; Bouzas-Mosquera, A.; Estévez-Loureiro, R.; Barge-Caballero, G.; López-Pérez, M.; Vázquez-González, Nás.; Castro-Beiras, A., 2014: Prognostic value of exercise-induced left ventricular systolic dysfunction in hypertensive patients without coronary artery disease. We sought to assess the prognostic value of exercise-induced left ventricular systolic dysfunction in hypertensive patients with normal resting echocardiography and absence of coronary artery disease. From our database of patients referred for tre...

Cohen, H., 1950: Methods and men in the teaching of clinical medicine. British Medical Journal 2(4677): 478-481

McCord, R.Patton.; Bulyk, M.L., 2008: Functional trends in structural classes of the DNA binding domains of regulatory transcription factors. The DNA-binding domain (DBD) structure of a regulatory transcription factor (TF) is important in determining its DNA sequence specificity, but it is unclear whether a relationship exists between DBD structure and general TF biological function or...

Cooper G.J.S.; Scott D.J.; Mickleson K.N.P.; Mercer W.H., 1985: Pregnancy complicated by non insulin dependent diabetes mellitus and type v hyperlipoproteinemia case report. Type V hyperlipoproteinaemia complicated a pregnancy in a 38 yr old Samoan multigravida with previous non-insulin dependent diabetes. The hypertriglyceridemia was associated with severe insulin resistance, non-acidotic ketosis and poor control of...

Boeve, B.F.; Dickson, D.W.; Olson, E.J.; Shepard, J.W.; Silber, M.H.; Ferman, T.J.; Ahlskog, J.E.; Benarroch, E.E., 2006: Insights into REM sleep behavior disorder pathophysiology in brainstem-predominant Lewy body disease. Rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia reflecting changes in the brain, but which specific neuronal networks are involved in human RBD pathogenesis has not yet been determined. To date, only one case of idiopathic R...

Meyerson, J.; Lechuga-Gomez, E.E.; Bigazzi, P.E.; Walfish, P.G., 1988: Polyglandular autoimmune syndrome: current concepts. The polyglandular autoimmune syndrome (PGAS) is characterized by the association of two or more endocrine disorders that are mediated by autoimmune mechanisms and usually lead to a hypofunctional state. In this review we classify the various types...

Bremond J.; Raphel C., 1987: Predictive validity of personality traits towards success at the end of the first year of medical studies. Intercorrelations were calculated between scores at a psychopathological inventory (Bremont IP 9) and the success or failure of medical students at the end of the first year of medical studies. As expected, some traits, e.g. Schizoidy, are unfavou...

Gheorghiu, E., 1975: The ecology and control of apple powdery mildew (Podosphaera leucotricha) in the Geoagiu fruit growing region of the Hunedoara district. Cv. Jonathan apple trees on M.4 rootstock had less mildew than those on other rootstocks, whereas those on M.16 were most severely attacked. An assessment of the mildew infection of Jonathan trees on 11 rootstocks is tabulated. The degree of attac...

Shimizu H.; Fujimoto T., 1990: Neuroblastoma cell lysis by gamma interferon activated monocytes from patients receiving chemotherapy. Proceedings of the American Association for Cancer Research Annual Meeting 31: 245