+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Patient with Hansen disease and lepromatous reaction with predominant neural involvement

, : Patient with Hansen disease and lepromatous reaction with predominant neural involvement. Neurologia 13(1): 41-44

We describe a patient with a diagnosis of Hansen's disease borderline type, presenting as cutaneous lesions and silent multineuritis. Samples of nasal mucus, earlobe and cutaneous lesions were positive for acid-fast bacilli. He was given treatment with rifampin, dapsone and clofazimine. Five years later, he developed fever, poliarthritis, orchitis and hepatic involvement. Searching for acid-fast bacilli in many cutaneous and mucosal locations was fruitfulness. Because of clinical suspicion of erythema nodosum leprosum, he was treated with steroids with improvement of his clinical picture, but subsequently he developed multineuritis with many sensitive symptoms. A high number of bacilli was seen in nerve biopsy. We comment on atypical features of clinical evolution and erythema nodosum leprosum, and emphasize the significance of large number of bacilli into peripheral nerve in contrast with their absence at other levels.


PMID: 9522583

Other references

Miyamoto, T., 1951: The effect of thyroid function on development of Yoshida sarcoma II. [Japanese text. Gan 42(2-4): 262-264

Peterson, D.S., 2006: Matrix-free methods for laser desorption/ionization mass spectrometry. Matrix assisted laser desorption/ionization (MALDI) is a soft ionization mass spectrometric method that has become a preeminent technique in the analysis of a wide variety of compounds including polymers and proteins. The main drawback of MALDI is...

Du, S.; Wang, Y.; Chen, L-Zhen.; Shi, W-Jing.; Ren, F-de.; Li, Y-Xiang.; Wang, J-Long.; Cao, D-Lin., 2012: A B3LYP and MP2(full) theoretical investigation into explosive sensitivity upon the formation of the molecule-cation interaction between the nitro group of 3,4-dinitropyrazole and H+, Li+, Na+, Be2+ or Mg2+. The explosive sensitivity upon the formation of molecule-cation interaction between the nitro group of 3,4-dinitropyrazole (DNP) and H(+), Li(+), Na(+), Be(2+) or Mg(2+) has been investigated using the B3LYP and MP2(full) methods with the 6-311++G...

Benson, D.L.; Schnapp, L.M.; Shapiro, L.; Huntley, G.W., 2000: Making memories stick: cell-adhesion molecules in synaptic plasticity. Synapses are adhesive junctions highly specialized for interneuronal signalling in the central nervous system. The strength of the synaptic signal can be modified (synaptic plasticity), a key feature of the cellular changes thought to underlie lea...

Nierop,K.G.J.; Filley,T.R., 2008: Simultaneous analysis of tannin and lignin signatures in soils by thermally assisted hydrolysis and methylation using 13C-labeled TMAH. Tannin, condensed and hydrolysable, and lignin are two of the most abundant natural biopolymers in the environment. Yet it is still not possible using one analytical technique to simultaneously track each of their dynamics in litter and soils. The...

McIntire, M.J.; Chronister, E.L., 2006: Characterization of tunneling systems in molecular versus polymer glasses by high-pressure photon echo spectroscopy. Intrinsic differences between tunneling two-level systems (TLSs) in molecular versus polymeric glasses are revealed by studying the effect of compression on TLS dynamics. Photon echo studies under variable low-temperature (1.1-2.3 K) and high-pres...

Petsche, H.; Marko, A., 1954: Photocell toposcope, a simple method for determination of field distribution and spread of electroencephalographic processes. Archiv für Psychiatrie und Nervenkrankheiten, Vereinigt Mit Zeitschrift für die Gesamte Neurologie und Psychiatrie 192(5): 447-462

Holden Gregory S.; Fleckenstein Martin, 1980: Geologic history of the Precambrian of the central Laramie Range, Wyoming. Guidebook - Wyoming Geological Association 31): 17-22

Novikova V.N., 1986: Neurohumoral regulation of the cardiovascular system and metabolic status in adolescents at a high risk for ischemic heart disease. Pediatriya (Moscow) (6): 35-38

Exton-Smith, A.N., 1971: Maintenance of health in old age. Transactions of the Medical Society of London 87: 175-184