geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Polyamines and cell growth: specific aspects in Amoeba proteus and in certain cancer cell lines


, : Polyamines and cell growth: specific aspects in Amoeba proteus and in certain cancer cell lines. Bulletin et Memoires de L'academie Royale de Medecine de Belgique 150(5-6): 252-7; Discussion 257-8

The differences between the metabolic schemes of polyamines can be the starting point to investigate the discovery of new antiparasitic or anticancer drugs which would be cell type specific. The studies, which were undertaken with the P388 cancer cells and Amoeba proteus, have shown that the pool of polyamine was very different in both cell types. Moreover, the cytotoxicity of putrescine, spermidine, spermine and 1-3 diaminopropane was found to be dependent of the activity of cell enzymes which could play a role to control cell proliferation by producing toxic metabolites.

US$29.90

PMID: 8696270


Other references

Murachi, Shiro, 1962: Symptoms appearing in the eye fundus of the goldfish affected by drugs. The fundus of the goldfish was sensitive to 34 kinds of drugs. Harmful effects of these drugs on the vitality of the fish could be successfully avoided by removing the fish into a normal rearing medium upon finding symptoms of the incipient stage....

Melo, A.C. de; Cota, B.B.; Oliveira, A.B. de; Braga, F.C., 2001: HPLC quantitation of kaurane diterpenes in Xylopia species. Xylopia frutescens is a tree native to the Brazilian Amazon whose seeds are rich in kaurenoic acid, a diterpene that showed in vitro activity against Trypanosoma cruzi. Aiming to find out alternative sources for kaurenoic acid, the content of some...

D.L.renzo, N.; Bozzao, L.; Antonelli, M.; Fortuna, A., 1981: Arnold-Chiari malformation detected by unenhanced multiplanar CT scan. Multiplanar computed tomographic (CT) scanning done without injection of contrast agent detected the nervous tissue abnormalities in 4 patients with Arnold-Chiari Malformation. Comparisons were made between traditional radiological studies and CT...

Grimes, Peter, 1998: African goshawk takes lourie. Bee Eater and ECWBS News y; 49(3): 32

Burnside, O.C., 1964: Influence of trifluralin placement and seed depth on shattercane control. In a greenhouse study, trifluralin at 1 and 2 pounds per acre was either applied to the surface of the soil or incorporated into the 0-1, 1-2 or 2-3 in. layer of soil. Shattercane (Sorghum vulgare) emergence was least for the 0-1 in. incorporation...

Selmeier A., 1982: A colony of small roots on the foraminifera Gypsina linearis in the Priabonian Limestone Alps. CFS: er Forschungsinstitut Senckenberg. 56; Pages 43-48. 1982.

Imada, C.; Harada, Y.; Kobayashi, T.; Hamada-Sato, N.; Watanabe, E., 2005: Degradation of ferric chelate of ethylenediaminetetraacetic acid by bacterium isolated from deep-sea stalked barnacle. Twenty strains of marine bacteria that degrade ferric chelate of ethylenediaminetetraacetic acid (Fe-EDTA) were isolated from among 117 strains collected from a marine environment. Among them strain 02-N-2, which was isolated from stalked barnacle...

Sikka, Dr, 1979: Mahanadi Projects action plans from 1898 to 1978 single to multi-level-objective-water resources development in Madhya Pradesh State, India. Papers World Congress on Water Resources(2): 896-904

Mitsiopoulos, N.; Lyons, W.; Ross, R., 1997: Magnetic resonance imaging and computerized tomography provide valid estimates of skeletal muscle by comparison to human cadaver sections. Medicine & Science in Sports & Exercise 29(5 SUPPL ): S38

Daniel, A.; Jacob, P., 1976: Periodontal preparation for fixed prostheses. II. Immobilization of remaining teeth. L' Information Dentaire 58(26): 23-27