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Preliminary studies for interaction of a cyclobutane thymine dimer region with its cognate antibody


, : Preliminary studies for interaction of a cyclobutane thymine dimer region with its cognate antibody. Nucleic Acids Symposium Series: 281-282

A monoclonal antibody (TDM-2) specific to a UV-induced cyclobutane pyrimidine dimer has previously been established. We investigated here the structural requirements of antigen recognition by the antibody using chemically synthesized antigen analogs. TDM-2 bound to the cis-syn, but not the trans-syn thymine dimer, and recognized not only the cyclobutane ring but also the 5'- or 3'-side phosphate groups flanking the cyclobutane dimer site. The antibody showed strong binding to photodimer-containing single stranded DNA but indicated little binding to double stranded DNA.

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PMID: 9586109


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Shibata, E.; Shindo, I.; Miyakawa, E.; Kido, N., 2016: Supplemental feeding of captive neonatal koalas (Phascolarctos cinereus). Koalas (Phascolarctos cinereus) are cautious animals, making supplemental feeding of neonates challenging because of disturbances to the normal routine. However, supplemental feeding is beneficial in improving juvenile nutrition using less formula...

Tvorogova, M.G., 2009: Lipids and lipoproteins. Laboratory diagnosis of lipid-transporting system disorders (a lecture). Klinicheskaia Laboratornaia Diagnostika: 21-32

Thomason, Ij, 1978: Integrating control of the sugarbeet cyst nematode. California agriculture: 32 (2) 23

Liu, K.; Yang, S.; Yeoman, C.; Homeyer, B.; Roberts, M.; Phillipson, J., 1990: The effect of seed source and media composition on the production of canthin-6-ones in cell suspension cultures of Brucea javanica. Planta medica 56(6): 632

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Abstracts., 1989: Program abstracts. 101st Session. Iowa Academy of Science. April 21-22, 1989. Buena Vista College. Journal of the Iowa Academy of Science, 962: A1-A38

Tzon, U., 1977: Hai-Bar: the organisation of national biblical wildlife reserves in Israel. International Zoo Yearbook, 17: 240-243

Benoliel, J.J.; Bourgoin, S.; Collin, E.; Mauborgne, A.; Pohl, M.; Thiebot, M.H.; Hamon, M.; Cesselin, F., 1994: Disappearance of the inhibitory but not of the excitatory effects of opioids on spinal CCK-containing neurons in morphine-tolerant rats. Neuropeptides 26(SUPPL 1): 47

Gogel G.N., 1971: Two types of accessory zircon in granites of eastern Kazakhstan. Izvestiya Akademii Nauk Kazakhskoy SSR, Seriya Geologicheskaya = Khabarlary Kazakh SSR, Fylym Akademiyasynyn: ges 63-70. 1971.