+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Risks of antibiotic treatment

, : Risks of antibiotic treatment. Bratislavske Lekarske Listy 103(7-8): 270-275

Adverse effects of antibiotics can cause a failure of antibiotic treatment. The authors give a survey of antibiotic toxicity manifestations, according to the target organ systems, with emphasis on identification of at-risk patients and on possible prevention of particular adverse effects. Although antibiotics belong to relatively safe pharmaceuticals, many of them can be a cause of a serious damage to the human organism. Beta-lactam antibiotics are considered the least dangerous. A considerable number of adverse effects, especially the dose-dependent ones, are preventable on condition that the risk factors, as the patient's age, functional capacity of eliminating organs (kidney, liver), associated diseases and simultaneous administration of drugs, are considered. In conclusion, the clinically significant drug interactions of antibiotics are pointed out, being of increasing importance especially in patients with multiple diseases and polypragmatic manner of treatment. (Tab. 2, Ref. 48.)


PMID: 12519001

Other references

Weinberg, M.; Davesne, J.; Prevot, A.R., 1932: Studies on the Standardization of the Anti-Gas Gangrene Sera. The importance of a uniform procedure and a definite known standard for titrating the antitoxic sera of the gas gangrene group of organisms is emphasized. The necessity for using mice for carrying out such titrations is apparent. The authors give...

Tamas, J.; Fekete, S.; Hegedus, M.; Kovari, L.; Andrasofszky, E., 1993: Biological activity of methionine derivatives. III. Comparative studies on the effect of methionine and methionine-hydroxy-analog in a broiler fattening trial. A model broiler fattening experiment was carried out in Tetra cock chicken between the age of 14 to 19 days to compare the biological effectiveness of methionine (MET) and the methionine-hydroxy-analog (2-hydroxy-4-methylthiobutanoic acid, HMB). B...

Armstrong-James, M.; Callahan, C.A.; Friedman, M.A., 1991: Thalamo-cortical processing of vibrissal information in the rat. I. Intracortical origins of surround but not centre-receptive fields of layer IV neurones in the rat S1 barrel field cortex. The receptive fields of cells restricted to the D1 cortical barrel territory in the S1 cortex of the rat were examined before and after substantial lesions of the D2 barrel. We tested 131 cells (N = 62, unlesioned controls; N = 69, lesioned animal...

Coe, T.; Nettleship, A.; Haggar, T., 2002: A specialist asthma service. Nursing Times 98(12): 48-51

Anonymous, 2013: Percutaneous transhepatic biliary draina assisted by real-time virtual sonography a retrospective study. Real-time virtual sonography (RVS) is a diagnostic imaging support system that can synchronize with ultrasound images in conjunction with computed tomography or magnetic resonance images using magnetic navigation system. RVS has been applied in cl...

Amadon, D., 1940: Hosts of the Cow-bird. Auk, 257

Singh, A.K.; Singh, K.P., 2003: Induced micromutation through gamma rays and EMS in okra Abelmoschus esculentus (L.) Moench. Seeds of 3 genotypes of okra (Parbhani Kranti, Hisar Unnat and Satdhari) were treated with gamma rays at 15, 30, 45 and 60 kR, and ethyl methanesulfonate (EMS) at 0.25, 0.5, 0.75 and 1%. The effects of these treatments in the M2 and M3 generations...

Taylor, K., 1916: The Mechanism Of Saline Dressings. British Medical Journal 2(2905): 321-324

V.G.rcia-Duen˜as; F.G.nzalez Lodeiro; A.J.baloy; J.M.M.rtinez Martinez; M.O.ozco, 1991: The movement across the Nevado-Filabride shear zones and the convergence of Europe and Africa (Betic Orogen). Tectonophysics 191(3-4): 420

Hatcher, J.F.; Bryan, G.T., 1985: Factors affecting the mutagenic activity of quercetin for Salmonella typhimurium TA98: metal ions, antioxidants and pH. The mutagenic activity of quercetin for Salmonella typhimurium TA98 was inhibited by addition of metal salts. MnCl2 was a potent inhibitor, followed by CuCl2, FeSO4, and FeCl3, the probable mechanism being facilitated catalytic oxidation of querce...