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Routine screening for local recurrence following breast-conserving therapy for cancer with dynamic contrast-enhanced magnetic resonance imaging of the breast


, : Routine screening for local recurrence following breast-conserving therapy for cancer with dynamic contrast-enhanced magnetic resonance imaging of the breast. Annals of Surgical Oncology 5(3): 265-270

Dynamic contrast-enhanced magnetic resonance imaging (MRI) of the breast is highly sensitive for the diagnosis of primary breast malignancy. We investigated the clinical application of dedicated dynamic breast MR for routine screening for local recurrence following breast-conserving therapy. Patients underwent a single dynamic MR of the breast routinely in the period 1 to 2 years following treatment, or earlier if recurrence was suspected. A biopsy was performed if there was suspicion of recurrence on MR. One hundred and five patients with a median age of 58 years (range 50 to 65 years) were recruited for the study. Sixteen biopsies were performed and nine recurrences were confirmed histologically. Patients not undergoing biopsy have been followed up for a median of 341 days (range 168 to 451 days) following the MR. The sensitivity for clinical examination, mammography, examination combined with mammography, and MRI alone for the detection of recurrent cancer were 89%, 67%, 100%, and 100%, respectively, and the specificity was 76%, 85%, 67%, and 93%. Combined clinical examination and mammography are as sensitive as dedicated dynamic MR of the breast for the detection of locoregional recurrence, but breast MRI is associated with a far greater specificity. Therefore, dedicated dynamic breast MRI should be used when there is clinical or mammographic suspicion of recurrence to confirm or refute its presence.

US$29.90

PMID: 9607630


Other references

Karlawish, J.H.; Quill, T.; Meier, D.E., 1999: A consensus-based approach to providing palliative care to patients who lack decision-making capacity. ACP-ASIM End-of-Life Care Consensus Panel. American College of Physicians-American Society of Internal Medicine. Making palliative care decisions for a patient who lacks decision-making capacity presents several challenges. Other people, such as family and caregivers, must choose for the patient. The goals and values of these decision makers may conflict wit...

Nagar, S.K., 1967: Parthenogenesis in Dermacentor variabilis (Say). When Dermacentor variabilis (Say) was reared on rabbits in the laboratory, it was found that some of the eggs laid by unmated females hatched. This is the first record of parthenogenesis in this tick; it was not known whether reproduction was thel...

Josnin, J.-Yves; Gallino, S., 2008: Interpretation of a pumping test conducted in the mixing zone between a thermal aquifer and a surface aquifer using physico-chemical parameters monitoring. The mixing between deep waters with thermal characteristics and surface water is common in French alpine regions. In the case of thermal baths of Aix-Marlioz, thermal waters from a "thermo-siphon" diffuse, after crossing an aquitard, int...

Wang, L.; Baeyens, W.R.G.; Van Der Weken, G.; Garcia Campana, A.M.; Zhang, X.R.; Smet, E., 2000: Oxidative chemiluminescence emission from trimipramine optimized by flow injection. Luminescence (Chichester) 15(2): 128-129, March-April

Bruns, W.; Debong, B.; Andreas, M., 1998: The new transplantation law. What must hospital physicians observe?. Der Chirurg; Zeitschrift für Alle Gebiete der Operativen Medizen 69(3): 80-83

Havlicek Vladimir, 1998: Prague Basin; Ordovician. Pages 41-79 1998

Erker, Richard, 1958: Centenary of Karst reforestation in Slovenia. In 1957, 100 years had passed since the death of Josef Ressel, inventor of the ship-propeller and pioneer of Karst reforestation, and in 1959, 100 years have elapsed since the first successful large-scale forestation, with Pinus nigra, at Bazovica...

Tardiff, K., 1981: The risk of assaultive behavior in suicidal patients. This study assessed the occurrence of assaultive behavior in a group of suicidal patients who were in psychiatric hospitals, many for long periods of time. Of the 94 suicidal patients, 42 (45%) patients physically assaulted other persons at least...

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