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The joint action of nitrates and gamma radiation on the blood plasma proteinase-inhibiting and antioxidative systems in rats


, : The joint action of nitrates and gamma radiation on the blood plasma proteinase-inhibiting and antioxidative systems in rats. Radiatsionnaia Biologiia, Radioecologiia 37(3): 297-302

The separate and combine influence of nitrates (40 mg of natrium nitrate) 100 g of body mass during 60 days) and gamma radiation (3 Gy) on condition of proteolytic and antioxidative blood plasma systems of rats have been investigated. There are were increase of total proteolytic activity (TPA) on 3-day, adaptive increase of alpha-antiproteinase inhibitor (API) on 7- and 14-day after factors separate action and tendency to increase TPA together with the invariable content of API after combine influence. The decrease of alpha-2-macroglobulin level on 14-day after all influences and more significantly after combination of factors action have been also shown. The decrease of antioxidant system and system of free radicals inactivation have been observed.

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PMID: 9244515


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