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Transforming the genome to drug discovery

, : Transforming the genome to drug discovery. Drug Discovery Today 7(11): 583-584


PMID: 12047860

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Kellum Lewis Burnett, 1955: Memorial to Ermine Cowles Case (1871-1953). Proceedings of the Geological Society of America Pages 93-101

Lima, Sônia.Maria.Rolim.Rosa.; Aldrighi, Jé.Mendes.; Consolim-Colombo, F.Marciano.; Mansur,ádua.; Rubira, M.Custódio.; Krieger, E.Moacyr.; Ramires, Jé.Antonio.Franchini., 2005: Acute administration of 17beta-estradiol improves endothelium-dependent vasodilation in postmenopausal women. Objectives: Estrogen's effect on endothelial function in postmenopausal women with mild hypertension but no other cardiovascular risk factors remains unclear. This study investigated the effect of an acutely administered therapeutic/low dose...

Tsuchida, T.; Koga, R.; Fukatsu, T., 2004: Host plant specialization governed by facultative symbiont. This paper reports that, in Japan, the host plant specialization of the pea aphid (Acyrthosiphon pisum) is governed by a facultative gamma -proteobacterium, called pea aphid U-type symbiont (PAUS). Pea aphids in natural Japanese populations exhibi...

Herber, C.; Breit, B., 2007: Enantioselective total synthesis and determination of the absolute configuration of the 4,6,8,10,16,18-hexamethyldocosane from Antitrogus parvulus. The absolute and relative configuration of the hexamethyldocosane (1) isolated from the cuticula of Antitrogus parvulus was determined based on the total synthesis of both diastereomers 1a and 1b in enantiomerically pure form. The synthesis demons...

Hay, R.; MacRae, E.; Barber, D.; Khalil, M.; Demetrick, D.J., 2007: BRAF mutations in melanocytic lesions and papillary thyroid carcinoma samples identified using melting curve analysis of polymerase chain reaction products. Context. - Mutations of the proto-oncogene B-raf (BRAF) have been detected in melanocytic lesions and papillary carcinomas of the thyroid, and identification of these mutations could be useful in resolving some diagnostic problems.Objective. - To...

Drew, J.E.; Farquharson, A.J.; Vase, H.; Carey, F.A.; Steele, R.J.C.; Ross, R.A.; Bunton, D.C., 2015: Molecular Profiling of Multiplexed Gene Markers to Assess Viability of Ex Vivo Human Colon Explant Cultures. Human colon tissue explant culture provides a physiologically relevant model system to study human gut biology. However, the small (20-30 mg) and complex tissue samples used present challenges for monitoring tissue stability, viability, and prov...

Wang Zhonghao; W.X.ling; Zhang Shengguo, 1996: Implementation of production logging data base. Jianghan Shiyou Xueyuan Xuebao = Journal of the Jianghan Petroleum Institute 18(2): 55-59

Stepkowska E.T.; Perez Rodriguez J.L.; Justo A.; Sanchez Soto P.J.; Jefferis S.A., 1988: Possibility of feldspar formation in bentonite suspensions during storage, drying and/ or heating. Thermochimica Acta 135: 319-334