+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Unilateral multicystic dysplastic kidney disease: defining the natural history. Anglia Paediatric Nephrourology Group

, : Unilateral multicystic dysplastic kidney disease: defining the natural history. Anglia Paediatric Nephrourology Group. Acta Paediatrica 89(7): 811-813

Controversy exists as to what is the optimal management of antenatally detected multicystic dysplastic kidney disease (MCDK): conservative or operative. We report 70 (31M, 39F) children with unilateral MCDK in whom the initial micturating cystourethrography revealed vesicoureteric reflux into the contralateral kidney in 16/63 (25%). Involution of the MCDK kidney was noted at birth in 4 and occurred by 2 y of age in 11/46 (24%), with 16/46 (35%) showing a significant reduction in size. Of 21 children followed to 5 y, the MCDK had disappeared in 3 (14%) and 8 (38%) had shown a further reduction in size. No child has developed hypertension or proteinuria. Four children had urinary tract infections with lower tract symptoms, but no scarring of the normal hypertrophied kidney. We conclude that conservative management of unilateral MCDK is justified with long-term follow-up consisting of annual clinical review and ultrasound evaluation at 2, 5 and 10 y.


PMID: 10943963

Other references

Montenegro H.D.; Daly B.; Thompson K.; Rudy E.B.; Shiao S Y.P., 1992: Special care unit for chronically critically ill patients a randomized study. American Review of Respiratory Disease 145(4 PART 2): A85

Navar L.G.; Thomas C.E.; Bell P.D.; Adams F.F., 1978: Influence of vaso dilators on glomerular filtration dynamics in the dog. Kidney International 14(6): 772

Jia, Y-Yuan.; Zhang, Y-Hui.; Xu, J.; Feng, R.; Zhang, M-Shi.; Bu, X-He., 2015: A high-performance "sweeper" for toxic cationic herbicides: an anionic metal-organic framework with a tetrapodal cage. This communication reports a novel metal-organic framework exhibiting an excellent performance in adsorbing small toxic cationic herbicides, i.e. methyl viologen and diquat, with large adsorption capacities and ultratrace residue levels. To the be...

Zdilar, D.; Luntz-Leybman, V.; Frostholm, A.; Rotter, A., 1992: Differential expression of GABAA/benzodiazepine receptor beta 1, beta 2, and beta 3 subunit mRNAs in the developing mouse cerebellum. Gamma aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian cerebellum. Cerebellar granule, Purkinje, and deep nuclear neurons are known to receive GABAergic afferents. Since GABA exerts its inhibitory effects via GABA...

Farhat, M.Y.; Dingaan, B.; Fader, M.E.; Ramwell, P.W., 1995: Estradiol 17-beta protects against homocysteine-induced vascular injury in rat thoracic aorta. Journal of the American College of Cardiology 0(SPEC ISSUE): 72A

Ronco J.; Belzberg A.; Walley K.; Dodek P.; Russell J., 1989: Does diastolic dysfunction account for lower oxygen delivery in nonsurvivors of septic and non septic ards?. American Review of Respiratory Disease 139(4 PART 2): A19

Brown, D.J.H., 1977: Artificial intelligence a new discipline in the computer sciences a viewpoint. Some recent work in artificial intelligence [AI] concerning machine vision, game-playing and automatic language processing is reviewed and related to Turing's early requirements for an intelligent machine. The relationship between computer sc...

Joseph, R.; Pulimood, S.A.; Abraham, P.; John, G.T., 2013: Successful treatment of verruca vulgaris with Thuja occidentalis in a renal allograft recipient. Human papillomavirus-driven verruca vulgaris infection is common in solid organ transplant recipients and increases the risk for squamous cell carcinoma. The available treatment modalities have limited response. We report a renal allograft recipie...

Lopatina, NG.; Chesnokova, EG.; Ponomarenko, VV., 1989: Neurological and behavioural effects of kinurenins - kinurenic and xanturenic acids - in the bee Apis mellifera L. Studies have been made of the effects of kinurenins.sbd.kinurenic (1 .cntdot. 10-4-4 .cntdot. 10-4 M) and xanturenic (2 .cntdot. 10-4 and 3 .cntdot. 10-4 M) acids on excitability thresholds of the nerve-muscle preparation and sensitivity to diethy...

Sadun, E.H.; Lin, S.S.; Williams, J.E., 1958: Studies on the host parasite relationships to Schistosoma japonicum. I. The effect of single graded infections and the route of migration of schistosomula. Sadun et al. describe investigations on the effect of single infections with varied doses of Schistosoma japonicum cercariae on mice survival, and also on whether the schistosomulae reach their final sites through the circulatory system or through...